Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10137786 | 0.90 | TACR1 (0.41) | TACR1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL10174292 | 0.83 | HTR2A (0.57) | ALDH1A1EPHX1MAPT | |
| SCHEMBL10206351 | 0.81 | PIK3CA (0.49) | CES2RXRARXRBRXRGALDH1A1 | |
| SCHEMBL6492340 | 0.79 | IDO1 (0.48) | TACR1CES2RXRARXRBRXRG | |
| SCHEMBL6865708 | 0.78 | CES2 (0.52) | TACR1CES2RXRARXRBRXRG | |
| SCHEMBL504122 | 0.76 | RXRA (0.68) | TACR1CES2RXRARXRBRXRG | |
| SCHEMBL14791168 | 0.76 | TACR1 (0.39) | TACR1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL7640052 | 0.75 | TACR1 (0.46) | TACR1CES2RXRARXRBRXRG | |
| SCHEMBL3329702 | 0.75 | CES2 (0.48) | TACR1CES2RXRARXRBRXRG | |
| SCHEMBL5462785 | 0.75 | CES2 (0.48) | TACR1CES2RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9687832-B2 | Bifunctional organic catalysts | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-06-27 | — | — | US | disclosed |
| US-20150298109-A1 | BIFUNCTIONAL ORGANIC CATALYSTS | ISIS INNOVATION LIMITED (GB) | 2015-10-22 | — | — | US | disclosed |
| US-7595299-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2009-09-29 | — | — | US | disclosed |
| US-7592316-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |
| US-20070232549-A1 | Novel peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION | 2007-10-04 | — | — | US | disclosed |
| US-7244721-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2007-07-17 | — | — | US | disclosed |
| US-20070032433-A1 | Novel peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION CORVAS INTERNATIONAL, LTD. | 2007-02-08 | — | — | US | disclosed |
| US-7169760-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2007-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232549-A1 | Novel peptides as NS3-serine protease inhibitors of hepatitis C virus | HPN, TMPRSS15, VIP | TACR1 1070/4885CES2 1377/4885RXRA 4631/4885 |
| US-20150298109-A1 | BIFUNCTIONAL ORGANIC CATALYSTS | CCNL2, UBE2L3, ARL1 | TACR1 4417/4885CES2 1056/4885RXRA 3809/4885 |
| US-20070032433-A1 | Novel peptides as NS3-serine protease inhibitors of hepatitis C virus | HPN, TMPRSS15, VIP | TACR1 1070/4885CES2 1377/4885RXRA 4631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.