Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17581887 | 0.88 | HSP90AB1 (0.50) | HSP90AB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8824487 | 0.81 | ALDH1A1 (0.54) | ALOX5MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL17581889 | 0.81 | HSP90AB1 (0.44) | HSP90AB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL23395635 | 0.79 | NPC1 (0.55) | HSP90AB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28980172 | 0.79 | ALDH1A1 (0.47) | HSP90AB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28151481 | 0.79 | HSP90AB1 (0.43) | HSP90AB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11663656 | 0.79 | ALOX5 (0.41) | ALOX5CHRM2MEN1CHRM4CHRM5 | |
| SCHEMBL10209863 | 0.78 | HTT (0.51) | HSP90AB1MEN1CYP2C9KMT2AALDH1A1 | |
| SCHEMBL4741136 | 0.78 | CYP4F2 (0.56) | HSP90AB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL2875402 | 0.78 | TDP1 (0.56) | HSP90AB1KMT2AALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898247-B | Synthetic method of furan acetate compound | 中国科学院兰州化学物理研究所 | 2023-03-14 | — | — | CN | disclosed |
| CN-112898247-A | Synthetic method of furan acetate compound | 中国科学院兰州化学物理研究所 | 2021-06-04 | — | — | CN | disclosed |
| EP-1728793-B1 | 9-SUBSTITUTED 8-OXOADENINE COMPOUND | SUMITOMO DAINIPPON PHARMA CO LTD (JP) | 2016-02-03 | — | — | EP | disclosed |
| US-8354439-B2 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-15 | — | — | US | disclosed |
| US-20120178743-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-07-12 | — | — | US | disclosed |
| EP-1550662-B1 | ADENINE COMPOUND AND USE THEREOF | DAINIPPON SUMITOMO PHARMA CO (JP) | 2012-07-04 | — | — | EP | disclosed |
| US-8148371-B2 | Adenine compound and use thereof | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-04-03 | — | — | US | disclosed |
| US-8148371-B2 | Adenine compound and use thereof | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-04-03 | — | — | US | disclosed |
| US-20100256118-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | DAINIPPON SUMITOMO PHARMA CO.,LTD. (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20100256118-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | DAINIPPON SUMITOMO PHARMA CO.,LTD. (JP) | 2010-10-07 | — | — | US | disclosed |
| US-7754728-B2 | Adenine compound and use thereof | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-07-13 | — | — | US | disclosed |
| US-7754728-B2 | Adenine compound and use thereof | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20070238758-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | OTSUKA PHARMACEUTICAL CO., LTD. | 2007-10-11 | — | — | US | disclosed |
| US-20070105911-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | CHIHIRO MASATOSHI | 2007-05-10 | — | — | US | disclosed |
| US-4107178-A | Thioprene or furan derivatives and process for preparation thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1978-08-15 | — | — | US | disclosed |
| US-4086420-A | Thioprene or furan derivatives and process for preparation thereof | SAGAMI CHEMICAL RESEARCH CENTER (JA) | 1978-04-25 | — | — | US | disclosed |
| US-4051151-A | Thiophene derivatives and process for preparation thereof | SAGAMI CHEMICAL RESEARCH CENTER (JA) | 1977-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238758-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | IL2, IL1RN, SELL | ALOX5 396/4885HSP90AB1 1267/4885CHRM2 2702/4885 |
| US-20100256118-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | ADORA1, P2RY10, HRH4 | ALOX5 985/4885HSP90AB1 3615/4885CHRM2 49/4885 |
| US-20070105911-A1 | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion | IL2, IL1RN, SELL | ALOX5 394/4885HSP90AB1 1229/4885CHRM2 2714/4885 |
| US-20120178743-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | ADORA1, HRH4, P2RY10 | ALOX5 958/4885HSP90AB1 3261/4885CHRM2 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.