Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.56 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17581887 | 0.89 | HSP90AB1 (0.50) | CYP4F2CYP4A11HSP90AB1HTTALDH1A1 | |
| SCHEMBL17581889 | 0.81 | HSP90AB1 (0.44) | CYP4F2CYP4A11HSP90AB1HTTALDH1A1 | |
| SCHEMBL10174351 | 0.78 | ALOX5 (0.46) | CYP4F2CYP4A11HSP90AB1HTTALDH1A1 | |
| SCHEMBL15522967 | 0.78 | CES1 (0.47) | CYP4F2CYP4A11ALDH1A1KDM4EGAA | |
| SCHEMBL17077689 | 0.77 | ALDH1A1 (0.55) | CYP4F2CYP4A11HSP90AB1HTTALDH1A1 | |
| SCHEMBL17537987 | 0.77 | ALDH1A1 (0.48) | HTTALDH1A1KDM4EGAAHDAC1 | |
| SCHEMBL23395635 | 0.76 | NPC1 (0.55) | CYP4F2CYP4A11HSP90AB1HTTALDH1A1 | |
| SCHEMBL28151481 | 0.76 | HSP90AB1 (0.43) | CYP4F2CYP4A11HSP90AB1HTTALDH1A1 | |
| SCHEMBL28980172 | 0.76 | ALDH1A1 (0.47) | CYP4F2CYP4A11HSP90AB1HTTALDH1A1 | |
| SCHEMBL4741404 | 0.76 | CYP4F2 (0.36) | CYP4F2CYP4A11HSP90AB1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149110-A1 | BICYCLOR [2.2.1] HEPT-7-YLAMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASES AND CONDITIONS IN WHICH M3 MUSCARINIC RECEPTOR ACTIVITY AND BETA-ADRENERGIC ACTIVITY ARE IMPLICATED | ARGENTA DISCOVERY LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |
| WO-2008096127-A2 | BICYCLO[2.2.1]HEPT-7-YLAMINE DERIVATIVES AND THEIR USE AS M3 MUSCARINIC RECEPTOR MODULATORS | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |