Sugi Predict

Sugi Predict / Compounds / SCHEMBL10176059

SCHEMBL10176059

SCHEMBL10176059

C1=Cc2c(oc3c(-c4ccc5c(c4)c4cc(-c6cccc7c6oc6ccccc67)ccc4n5-c4cccc(-c5ccc6c7ccccc7c7ccccc7c6c5)c4)cccc23)CC1

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.40
▸ PRKDC P78527 4/20 0.37
▸ PRMT5 O14744 1/20 0.37
▸ WDR77 Q9BQA1 1/20 0.37
▸ GGPS1 O95749 1/20 0.34
▸ PTGES2 Q9H7Z7 1/20 0.34
▸ ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL780850 0.87 ALOX5 (0.51) ALOX5PRKDCPRMT5WDR77GGPS1
SCHEMBL1709197 0.86 PRKDC (0.33) PRKDCPRMT5WDR77ATM
SCHEMBL25564979 0.85 KDM4E (0.33) PRKDCATM
SCHEMBL781463 0.85 ALOX5 (0.49) ALOX5PRKDCPRMT5WDR77GGPS1
SCHEMBL788706 0.84 ALOX5 (0.35) ALOX5PRKDCPRMT5WDR77
SCHEMBL788407 0.84 ALOX5 (0.36) ALOX5PRKDCPRMT5WDR77
SCHEMBL12153567 0.82 ALOX5 (0.51) ALOX5PRKDCPRMT5WDR77GGPS1
SCHEMBL13830074 0.81 ALOX5 (0.52) ALOX5PRKDCPRMT5WDR77GGPS1
SCHEMBL22178688 0.81 ALOX5 (0.34) ALOX5PRKDCPRMT5WDR77GGPS1
SCHEMBL781064 0.81 ALOX5 (0.49) ALOX5PRKDCPRMT5WDR77GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012039262-A1 CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT MATERIAL AND ORGANIC SEMICONDUCTOR MATERIAL SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-29 — — WO disclosed
Send feedback