SCHEMBL1709197

SCHEMBL1709197

C1=Cc2c(oc3c(-c4cccc(-c5cccc(-c6cccc(-c7cccc(-n8c9ccccc9c9cc(-n%10c%11ccccc%11c%11ccccc%11%10)ccc98)c7)c6)c5)c4)cccc23)CC1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PRKDC P78527 1/20 0.33
▸ PRMT5 O14744 1/20 0.31
▸ WDR77 Q9BQA1 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.30
▸ ATM Q13315 1/20 0.30
▸ L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25564979 0.92 KDM4E (0.33) PRKDCKDM4EATML3MBTL1
SCHEMBL10176059 0.86 ALOX5 (0.40) PRKDCPRMT5WDR77ATM
SCHEMBL21599396 0.83 PRKDC (0.33) PRKDCKDM4EL3MBTL1
SCHEMBL18597478 0.81 — —
SCHEMBL21993183 0.81 PLA2G2A (0.38) PRKDCKDM4EATML3MBTL1
SCHEMBL12138211 0.81 KDM4E (0.32) KDM4EATML3MBTL1
SCHEMBL23616463 0.81 ALOX5 (0.38) PRKDCPRMT5WDR77ATM
SCHEMBL18639440 0.80 — —
SCHEMBL25705768 0.80 KDM4E (0.37) KDM4EATML3MBTL1
SCHEMBL25766597 0.80 KDM4E (0.37) PRKDCKDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120086329-A1 Novel 3, 9-Linked Oliogocarbazole-Based Hosts, Containing DBT and DBF Fragments, Separated by Aromatic Spacers Universal Disolay Corporation (US) 2012-04-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120086329-A1 Novel 3, 9-Linked Oliogocarbazole-Based Hosts, Containing DBT and DBF Fragments, Separated by Aromatic Spacers DBF4, OGFOD1, DDT PRKDC 2338/4885PRMT5 3336/4885WDR77 480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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