Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10145456 | 0.80 | MAPT (0.57) | MAPTALDH1A1MEN1USP2LMNA | |
| SCHEMBL10176070 | 0.75 | MAPT (0.39) | MAPTALDH1A1MEN1USP2LMNA | |
| SCHEMBL10176069 | 0.74 | MAPT (0.58) | MAPTALDH1A1MEN1USP2LMNA | |
| SCHEMBL30378455 | 0.71 | MAPT (0.66) | MAPTALDH1A1MEN1USP2LMNA | |
| SCHEMBL13914139 | 0.67 | MAPT (0.64) | MAPTALDH1A1MEN1USP2LMNA | |
| SCHEMBL7221761 | 0.66 | MEN1 (0.45) | MAPTALDH1A1MEN1USP2LMNA | |
| SCHEMBL10145450 | 0.65 | MAPT (0.58) | MAPTALDH1A1MEN1USP2LMNA | |
| SCHEMBL20841466 | 0.64 | MAPT (0.51) | MAPTALDH1A1MEN1USP2LMNA | |
| SCHEMBL12560103 | 0.64 | ALDH1A1 (0.40) | MAPTALDH1A1MEN1USP2LMNA | |
| SCHEMBL10145464 | 0.63 | MAPT (0.53) | MAPTALDH1A1MEN1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114904-B2 | Luminescence quenchers and fluorogenic probes for detection of reactive species | Versitech Limited & Morningside Ventures Limited (CN) | 2012-02-14 | — | — | US | disclosed |