Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10178012 | 1.00 | TOP2A (0.37) | TOP2AHDAC1 | |
| SCHEMBL12762680 | 1.00 | TOP2A (0.37) | TOP2AHDAC1 | |
| SCHEMBL10178214 | 0.91 | TOP2A (0.30) | TOP2A | |
| SCHEMBL16728051 | 0.91 | TOP2A (0.30) | TOP2A | |
| SCHEMBL889603 | 0.91 | TOP2A (0.30) | TOP2A | |
| SCHEMBL12570200 | 0.89 | TOP2A (0.41) | TOP2AHDAC1 | |
| SCHEMBL12762679 | 0.89 | TOP2A (0.41) | TOP2AHDAC1 | |
| SCHEMBL17476052 | 0.89 | TOP2A (0.41) | TOP2AHDAC1 | |
| SCHEMBL17466588 | 0.86 | — | — | |
| SCHEMBL889667 | 0.80 | TOP2A (0.34) | TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10697009-B2 | Nucleotide analogs for sequencing | IBIS BIOSCIENCES INC. (US) | 2020-06-30 | — | — | US | disclosed |
| US-10428379-B2 | Nucleotide analogs for sequencing | IBIS BIOSCIENCES, INC. (US) | 2019-10-01 | — | — | US | disclosed |
| EP-2970366-B1 | NUCLEOTIDE ANALOGS FOR SEQUENCING | IBIS BIOSCIENCES INC (US) | 2019-01-16 | — | — | EP | disclosed |
| US-20160032376-A1 | NUCLEOTIDE ANALOGS FOR SEQUENCING | IBIS BIOSCIENCES, INC. | 2016-02-04 | — | — | US | disclosed |
| US-9023316-B2 | Synthesis of 18F-labeled tracers in hydrous organic solvents | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-8148503-B2 | Nucleotides and nucleosides and methods for their use in DNA sequencing | LASERGEN, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-7964352-B2 | 3′-OH unblocked nucleotides and nucleosides, base modified with labels and photocleavable, terminating groups and methods for their use in DNA sequencing | LASERGEN, INC. (US) | 2011-06-21 | — | — | US | disclosed |
| US-20100041041-A1 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | AGILENT TECHNOLOGIES, INC. | 2010-02-18 | — | — | US | disclosed |
| US-20090081686-A1 | PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | AGILENT TECHNOLOGIES, INC. | 2009-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041041-A1 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | UNG, NT5C2, NT5E | TOP2A 117/4885HDAC1 4499/4885 |
| US-10428379-B2 | Nucleotide analogs for sequencing | RNGTT, POLRMT, NT5C3B | TOP2A 492/4885HDAC1 4875/4885 |
| US-10697009-B2 | Nucleotide analogs for sequencing | RNGTT, POLRMT, NT5C3B | TOP2A 492/4885HDAC1 4875/4885 |
| US-20160032376-A1 | NUCLEOTIDE ANALOGS FOR SEQUENCING | RNGTT, POLRMT, NT5C3B | TOP2A 492/4885HDAC1 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.