Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10507474 | 0.83 | ALDH1A1 (0.63) | TSHRCASP1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL1431441 | 0.79 | ALDH1A1 (0.48) | TSHRCASP1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL1128472 | 0.79 | SRD5A2 (0.51) | CASP1ALDH1A1NR4A1TP53CYP1A2 | |
| SCHEMBL2911184 | 0.78 | TSHR (0.63) | TSHRCASP1SMN1; SMN2ALDH1A1MYC | |
| SCHEMBL2770320 | 0.77 | TSHR (0.68) | TSHRCASP1SMN1; SMN2ALDH1A1MYC | |
| SCHEMBL111279 | 0.77 | TSHR (1.00) | TSHRCASP1SMN1; SMN2ALDH1A1MYC | |
| SCHEMBL27793256 | 0.77 | ALDH1A1 (0.46) | TSHRCASP1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL1015578 | 0.76 | ABL1 (0.50) | TSHRCASP1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL9174867 | 0.76 | ALDH1A1 (0.55) | CASP1ALDH1A1CYP1A2MAPTKDM4E | |
| SCHEMBL2415209 | 0.76 | ALDH1A1 (0.61) | TSHRSMN1; SMN2ALDH1A1MYCCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3859804-B1 | SEMICONDUCTOR DEVICE HAVING QUANTUM DOTS | CANON KK (JP) | 2024-08-07 | — | — | EP | claimed |
| US-4826888-A | STORAGE STABLE, DISCOLORATION INHIBITION | MITSUBISHI RAYON CO., LTD. (JP) | 1989-05-02 | — | — | US | claimed |
| US-12245446-B2 | Semiconductor device having quantum dots, display device, imaging system, and moving body | CANON KABUSHIKI KAISHA (JP) | 2025-03-04 | — | — | US | disclosed |
| EP-3859804-B1 | SEMICONDUCTOR DEVICE HAVING QUANTUM DOTS | CANON KK (JP) | 2024-08-07 | — | — | EP | disclosed |
| US-20240116872-A1 | PYRIDYL INHIBITORS FOR HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2024-04-11 | — | — | US | disclosed |
| US-20230265054-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2023-08-24 | — | — | US | disclosed |
| CN-113285024-A | Semiconductor device having quantum dots, display device, imaging system, and moving object | 佳能株式会社 | 2021-08-20 | — | — | CN | disclosed |
| US-20210242416-A1 | SEMICONDUCTOR DEVICE HAVING QUANTUM DOTS, DISPLAY DEVICE, IMAGING SYSTEM, AND MOVING BODY | CANON KABUSHIKI KAISHA (JP) | 2021-08-05 | — | — | US | disclosed |
| EP-3859804-A2 | SEMICONDUCTOR DEVICE HAVING QUANTUM DOTS | CANON KABUSHIKI KAISHA (JP) | 2021-08-04 | — | — | EP | disclosed |
| US-20210070707-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2021-03-11 | — | — | US | disclosed |
| US-10894775-B2 | Piperidine derivatives as liver X receptor beta agonists, compositions, and their use | MERCK SHARP & DOHME CORP. (US) | 2021-01-19 | — | — | US | disclosed |
| EP-1789390-A2 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | Genentech, Inc. (US) | 2007-05-30 | — | — | EP | disclosed |
| US-20060063779-A1 | Pyridyl inhibitors of hedgehog signalling | CURIS ROYALTY LLC | 2006-03-23 | — | — | US | disclosed |
| WO-2006028958-A2 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2006-03-16 | — | — | WO | disclosed |
| WO-2001056982-A1 | VITAMIN D-DERIVATIVES AND THEIR USE IN TREATING OSTEOPOROSIS AND RELATED BONE DISORDERS | LEO PHARMA A/S (DK) | 2001-08-09 | — | — | WO | disclosed |
| US-5047442-A | Photopolymerizable composition based on a vinyl compound, a sulfur-containing compound and an alpha-diketone | MITSUBISHI RAYON COMPANY LIMITED (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0201903-B1 | PHOTOPOLYMERIZABLE COMPOSITION | MITSUBISHI RAYON CO., LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |
| US-4826888-A | STORAGE STABLE, DISCOLORATION INHIBITION | MITSUBISHI RAYON CO., LTD. (JP) | 1989-05-02 | — | — | US | disclosed |
| US-4777190-A | Photopolymerizable composition based on a vinyl compound, a sulfur-containing compound and an α-diketone | MITSUBISHI RAYON COMPANY LIMITED (JP) | 1988-10-11 | — | — | US | disclosed |
| EP-0201903-A2 | Photopolymerizable composition | MITSUBISHI RAYON CO., LTD. (JP) | 1986-11-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10894775-B2 | Piperidine derivatives as liver X receptor beta agonists, compositions, and their use | NR1H2, NR1H3, ADRB1 | TSHR 525/4885CASP1 2530/4885SMN1; SMN2 3587/4885 |
| US-20230265054-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | SHH, GLI1, SMO | TSHR 421/4885CASP1 2749/4885SMN1; SMN2 4094/4885 |
| US-20240116872-A1 | PYRIDYL INHIBITORS FOR HEDGEHOG SIGNALLING | SHH, GLI1, SMO | TSHR 453/4885CASP1 2694/4885SMN1; SMN2 4106/4885 |
| US-20210070707-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | SHH, GLI1, SMO | TSHR 421/4885CASP1 2749/4885SMN1; SMN2 4094/4885 |
| US-20060063779-A1 | Pyridyl inhibitors of hedgehog signalling | SHH, GLI1, SMO | TSHR 421/4885CASP1 2749/4885SMN1; SMN2 4094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.