SCHEMBL10179568

SCHEMBL10179568

CC(C)c1cccc(S(=O)(=O)C(F)C(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 3/20 0.41
CA2 P00918 5/20 0.41
HDAC4 P56524 2/20 0.41
HDAC8 Q9BY41 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MDM4 O15151 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CA1 P00915 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
TYR P14679 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
CA5A P35218 1/20 0.41
HTT P42858 1/20 0.41
MDM2 Q00987 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10180813 0.85 HDAC4 (0.47) KAT6ACA2HDAC4HDAC8ALDH1A1
SCHEMBL21471341 0.83 KAT6A (0.44) KAT6ACA2HDAC4HDAC8KDM4E
SCHEMBL25442623 0.80 PGR (0.43) KAT6ACA2HDAC4HDAC8KDM4E
SCHEMBL12005159 0.79 ALDH1A1 (0.44) KAT6ACA2KDM4EALDH1A1CA1
SCHEMBL26452903 0.79 CA2 (0.55) KAT6ACA2HDAC4HDAC8KDM4E
SCHEMBL11300578 0.79 SMN1; SMN2 (0.52) KAT6ACA2HDAC4HDAC8KDM4E
SCHEMBL84445 0.77 ALDH1A1 (0.47) KAT6ACA2HDAC4HDAC8KDM4E
SCHEMBL958495 0.76 ALDH1A1 (0.46) KAT6ACA2HDAC4HDAC8KDM4E
SCHEMBL84614 0.76 CA2 (0.61) CA2HDAC4HDAC8KDM4EMDM4
SCHEMBL11801670 0.76 ALDH1A1 (0.52) KAT6ACA2HDAC4HDAC8KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 US disclosed
US-20120219866-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
EP-2475041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME Mitsubishi Chemical Corporation (JP) 2012-07-11 EP disclosed