SCHEMBL10179872

SCHEMBL10179872

CCS(=O)(=O)c1ccccc1C1CCCC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.45
HSD11B1 P28845 2/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.40
PSIP1 O75475 1/20 0.39
HTR1D P28221 2/20 0.39
HTR1B P28222 2/20 0.39
CTSB P07858 1/20 0.37
DRD3 P35462 2/20 0.36
ALDH1A1 P00352 2/20 0.36
USP2 O75604 1/20 0.36
CYP1A2 P05177 1/20 0.36
HTR1A P08908 1/20 0.36
ADRA2A P08913 1/20 0.36
CYP2D6 P10635 1/20 0.36
CHRM1 P11229 1/20 0.36
CYP2C9 P11712 1/20 0.36
DRD1 P21728 1/20 0.36
TBXA2R P21731 1/20 0.36
PTGS1 P23219 1/20 0.36
SLC6A2 P23975 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10179841 0.98 PTGS2 (0.48) PTGS2HSD11B1PTGDR2PSIP1HTR1D
SCHEMBL10181659 0.83 TSHR (0.50) PTGS2PTGDR2ALDH1A1USP2CYP1A2
SCHEMBL10180103 0.81 PTGS2 (0.55) PTGS2HSD11B1PTGDR2ALDH1A1HTR6
SCHEMBL10179567 0.81 TSHR (0.49) PTGS2PTGDR2ALDH1A1USP2CYP1A2
SCHEMBL10179999 0.81 HSD11B1 (0.48) PTGS2HSD11B1PTGDR2ALDH1A1KMT2A
SCHEMBL10180795 0.80 ALDH1A1 (0.42) PTGS2HSD11B1PTGDR2ALDH1A1KMT2A
SCHEMBL10181236 0.80 HSD11B1 (0.43) PTGS2HSD11B1PTGDR2DRD3USP2
SCHEMBL10192344 0.80 PTGS2 (0.58) PTGS2HSD11B1PTGDR2ALDH1A1KMT2A
SCHEMBL10180538 0.79 PTGS2 (0.49) PTGS2HSD11B1PTGDR2ALDH1A1CYP2C9
SCHEMBL10180451 0.79 PTGS2 (0.43) PTGS2HSD11B1PTGDR2DRD3DRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 US disclosed
US-20120219866-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
EP-2475041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME Mitsubishi Chemical Corporation (JP) 2012-07-11 EP disclosed