SCHEMBL10180173

SCHEMBL10180173

C=C(C)C(=O)OC1C2CC3C1OC(=O)C3(C(=O)Cl)C2

nearest known ligand 0.31

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
HTT P42858 1/20 0.31
RECQL P46063 1/20 0.31
RAB9A P51151 1/20 0.31
ATM Q13315 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL686170 0.90 KDM4E (0.31) KDM4ENPC1POLBMAPTPKM
SCHEMBL17534907 0.89 KDM4E (0.30) KDM4ENPC1POLBMAPTPKM
SCHEMBL10293989 0.88 ALDH1A1 (0.30)
SCHEMBL17534903 0.86
SCHEMBL10293987 0.85 KDM4E (0.31) KDM4ENPC1POLBMAPTPKM
SCHEMBL1217987 0.84 KDM4E (0.31) KDM4ENPC1POLBMAPTPKM
SCHEMBL685840 0.82 KDM4E (0.32) KDM4ENPC1POLBMAPTPKM
SCHEMBL1218545 0.82 KDM4E (0.32) KDM4ENPC1POLBMAPTPKM
SCHEMBL18720924 0.82 KDM4E (0.32) KDM4ENPC1POLBMAPTPKM
SCHEMBL23651658 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8865389-B2 Actinic-ray- or radiation-sensitive resin composition, actinic-ray- or radiation-sensitive film therefrom and method of forming pattern FUJIFILM CORPORATION (JP) 2014-10-21 US disclosed
US-8865389-B2 Actinic-ray- or radiation-sensitive resin composition, actinic-ray- or radiation-sensitive film therefrom and method of forming pattern FUJIFILM CORPORATION (JP) 2014-10-21 US disclosed
US-20120171618-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING A PATTERN USING THE SAME FUJIFILM CORPORATION (JP) 2012-07-05 US disclosed
US-20120076997-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC-RAY- OR RADIATION-SENSITIVE FILM THEREFROM AND METHOD OF FORMING PATTERN FUJIFILM CORPORATION (JP) 2012-03-29 US disclosed