SCHEMBL1218545

SCHEMBL1218545

C=C(C)C(=O)OC1C2CC3C1OC(=O)C3(F)C2

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
HTT P42858 1/20 0.32
RECQL P46063 1/20 0.32
RAB9A P51151 1/20 0.32
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
OPRM1 P35372 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25690269 0.87 ALDH1A1 (0.32)
SCHEMBL25690273 0.86 THRB (0.32)
SCHEMBL685840 0.85 KDM4E (0.32) KDM4ENPC1POLBMAPTPKM
SCHEMBL18720924 0.85 KDM4E (0.32) KDM4ENPC1POLBMAPTPKM
SCHEMBL5666141 0.84
SCHEMBL1217987 0.84 KDM4E (0.31) KDM4ENPC1POLBMAPTPKM
SCHEMBL1217561 0.83 KDM4E (0.32) KDM4ENPC1POLBMAPTPKM
SCHEMBL686170 0.82 KDM4E (0.31) KDM4ENPC1POLBMAPTPKM
SCHEMBL10180173 0.82 KDM4E (0.31) KDM4ENPC1POLBMAPTPKM
SCHEMBL17534907 0.81 KDM4E (0.30) KDM4ENPC1POLBMAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210405530-A1 PHOTOSENSITIVE COMPOSITION FOR EUV LIGHT, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2021-12-30 US disclosed
US-8753793-B2 Method for producing resin solution for photoresist, photoresist composition, and pattern-forming method DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2014-06-17 US disclosed
US-8637623-B2 Monomer having electron-withdrawing substituent and lactone skeleton, polymeric compound, and photoresist composition DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2014-01-28 US disclosed
US-8530134-B2 Process for producing photoresist polymeric compounds DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2013-09-10 US disclosed
US-8470510-B2 Polymer for lithographic purposes and method for producing same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2013-06-25 US disclosed
US-20110244394-A1 METHOD FOR PRODUCING RESIN SOLUTION FOR PHOTORESIST, PHOTORESIST COMPOSITION, AND PATTERN-FORMING METHOD DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2011-10-06 US disclosed
US-20110065044-A1 POLYMER FOR LITHOGRAPHIC PURPOSES AND METHOD FOR PRODUCING SAME DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2011-03-17 US disclosed
US-20110040056-A1 PROCESS FOR PRODUCTION OF POLYMER DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2011-02-17 US disclosed
US-20100316954-A1 MONOMER HAVING LACTONE SKELETON, POLYMER COMPOUND AND PHOTORESIST COMPOSITION DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2010-12-16 US disclosed
US-20100297555-A1 MONOMER HAVING ELECTRON-WITHDRAWING SUBSTITUENT AND LACTONE SKELETON, POLYMERIC COMPOUND, AND PHOTORESIST COMPOSITION DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2010-11-25 US disclosed
US-20100297551-A1 PROCESS FOR PRODUCING PHOTORESIST POLYMERIC COMPOUNDS DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100297555-A1 MONOMER HAVING ELECTRON-WITHDRAWING SUBSTITUENT AND LACTONE SKELETON, POLYMERIC COMPOUND, AND PHOTORESIST COMPOSITION DCXR, RPS10, RRS1 KDM4E 860/4885NPC1 4387/4885POLB 2013/4885
US-20100316954-A1 MONOMER HAVING LACTONE SKELETON, POLYMER COMPOUND AND PHOTORESIST COMPOSITION RRS1, CNKSR1, LSS KDM4E 1628/4885NPC1 4646/4885POLB 3393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.