SCHEMBL10180280

SCHEMBL10180280

CS(=O)(=O)NC(CCl)C(CCl)NS(C)(=O)=O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28554113 0.70
SCHEMBL21210802 0.69 KDM4E (0.33) CA2
SCHEMBL13684887 0.67 ADAM17 (0.35) CA2
SCHEMBL12863139 0.67 ALOX5AP (0.35) CA2
SCHEMBL16907684 0.67 ALDH1A1 (0.37) CA2
SCHEMBL2355870 0.64
SCHEMBL20748356 0.64
SCHEMBL824194 0.63
SCHEMBL12066041 0.63 CA2 (0.33) CA2
SCHEMBL7254253 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2474528-B1 Antineoplasic compounds and pharmaceutical compositions thereof CT INGENIERIA GENETICA BIOTECH (CU) 2014-09-24 EP claimed
EP-2474528-A1 Antineoplasic compounds and pharmaceutical compositions thereof Centro De Ingenieria Genetica Y Biotecnologia (CU) 2012-07-11 EP claimed