Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | CNR2 | P34972 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.55 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.55 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.55 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.55 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18240151 | 0.72 | SOAT2 (0.86) | CNR1ALDH1A1MAPTHPGDCNR2 | |
| SCHEMBL18240149 | 0.72 | SOAT2 (0.86) | CNR1ALDH1A1MAPTHPGDCNR2 | |
| SCHEMBL3154754 | 0.72 | CNR1 (0.71) | CNR1ALDH1A1MAPTHPGDCNR2 | |
| SCHEMBL3634730 | 0.72 | CNR1 (0.71) | CNR1ALDH1A1MAPTHPGDCNR2 | |
| SCHEMBL3634728 | 0.72 | CNR1 (0.71) | CNR1ALDH1A1MAPTHPGDCNR2 | |
| SCHEMBL1395702 | 0.71 | CNR1 (1.00) | CNR1ALDH1A1MAPTHPGDCNR2 | |
| SCHEMBL157919 | 0.71 | CNR1 (1.00) | CNR1ALDH1A1MAPTHPGDCNR2 | |
| SCHEMBL6705877 | 0.71 | CNR1 (1.00) | CNR1ALDH1A1MAPTHPGDCNR2 | |
| SCHEMBL5528061 | 0.70 | CNR1 (0.73) | CNR1ALDH1A1MAPTHPGDCNR2 | |
| SCHEMBL15007736 | 0.70 | CNR1 (0.90) | CNR1ALDH1A1MAPTHPGDCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636335-B1 | COMPOSITIONS AND METHODS FOR INHIBITING AN ISOFORM OF HUMAN MANGANESE SUPEROXIDE DISMUTASE | MITO TEK LLC (US) | 2012-07-11 | — | — | EP | claimed |