Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984567 | 1.00 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL6984581 | 0.85 | HSD17B10 (0.37) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL10181868 | 0.85 | HSD17B10 (0.37) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL6983873 | 0.80 | ALDH1A1 (0.33) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL18948300 | 0.80 | KDM4E (0.42) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL14724993 | 0.78 | LMNA (0.33) | HSD17B10 | |
| SCHEMBL14725022 | 0.76 | KDM4E (0.31) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL6983722 | 0.76 | KDM4E (0.31) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL12809034 | 0.70 | KDM4E (0.46) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL23598403 | 0.69 | KDM4E (0.34) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097718-B2 | 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof | ANADYS PHARMACEUTICALS, INC. (US) | 2012-01-17 | — | — | US | disclosed |