Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CCKAR | P32238 | 2/20 | 0.30 |
| ▸ | CCKBR | P32239 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10183738 | 0.92 | OPRM1 (0.40) | OPRM1OPRK1OPRL1MEN1KMT2A | |
| SCHEMBL10184200 | 0.86 | OPRM1 (0.38) | OPRM1OPRK1OPRL1HRH3MEN1 | |
| SCHEMBL10184028 | 0.86 | OPRM1 (0.35) | OPRM1OPRK1OPRL1 | |
| SCHEMBL10184169 | 0.85 | ALDH1A1 (0.37) | OPRM1OPRK1OPRL1NPSR1MEN1 | |
| SCHEMBL10183245 | 0.85 | OPRM1 (0.39) | OPRM1OPRK1OPRL1MEN1KMT2A | |
| SCHEMBL10184168 | 0.83 | OPRM1 (0.37) | OPRM1OPRK1OPRL1MEN1KMT2A | |
| SCHEMBL10183969 | 0.82 | OPRM1 (0.37) | OPRM1OPRK1OPRL1NPSR1MEN1 | |
| SCHEMBL10185666 | 0.82 | OPRM1 (0.36) | OPRM1OPRK1OPRL1NPSR1MEN1 | |
| SCHEMBL10185971 | 0.82 | OPRM1 (0.36) | OPRM1OPRK1OPRL1CCKBR | |
| SCHEMBL10183736 | 0.81 | OPRM1 (0.33) | OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009678-A1 | THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHOD OF USE | AGIOS PHARMACEUTICALS, INC. (US) | 2012-01-19 | — | — | WO | disclosed |