Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10184169 | 0.89 | ALDH1A1 (0.37) | OPRM1OPRK1OPRL1ALDH1A1KDM4E | |
| SCHEMBL10183738 | 0.88 | OPRM1 (0.40) | OPRM1OPRK1OPRL1ALDH1A1KDM4E | |
| SCHEMBL10183245 | 0.86 | OPRM1 (0.39) | OPRM1OPRK1OPRL1ALDH1A1KDM4E | |
| SCHEMBL10183752 | 0.83 | OPRM1 (0.37) | OPRM1OPRK1OPRL1MEN1KMT2A | |
| SCHEMBL10183969 | 0.83 | OPRM1 (0.37) | OPRM1OPRK1OPRL1ALDH1A1KDM4E | |
| SCHEMBL10185971 | 0.82 | OPRM1 (0.36) | OPRM1OPRK1OPRL1ALDH1A1KDM4E | |
| SCHEMBL10185666 | 0.82 | OPRM1 (0.36) | OPRM1OPRK1OPRL1ALDH1A1KDM4E | |
| SCHEMBL10184200 | 0.82 | OPRM1 (0.38) | OPRM1OPRK1OPRL1ALDH1A1KDM4E | |
| SCHEMBL10183736 | 0.82 | OPRM1 (0.33) | OPRM1OPRK1OPRL1IDH1 | |
| SCHEMBL10184181 | 0.82 | OPRM1 (0.35) | OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009678-A1 | THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHOD OF USE | AGIOS PHARMACEUTICALS, INC. (US) | 2012-01-19 | — | — | WO | disclosed |