Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10272436 | 0.82 | KMT2A (0.77) | KMT2AKDM4ELMNAALDH1A1RAB9A | |
| SCHEMBL13267211 | 0.76 | KMT2A (0.60) | KMT2AKDM4ELMNAALDH1A1RAB9A | |
| SCHEMBL28162774 | 0.75 | KMT2A (0.56) | KMT2AKDM4ELMNAALDH1A1RAB9A | |
| SCHEMBL7705653 | 0.75 | ALDH1A1 (0.77) | KMT2AKDM4ELMNAALDH1A1RAB9A | |
| SCHEMBL28162775 | 0.74 | KMT2A (0.58) | KMT2AKDM4ELMNAALDH1A1RAB9A | |
| SCHEMBL5095146 | 0.74 | KMT2A (0.67) | KMT2AKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL14045111 | 0.74 | KMT2A (0.67) | KMT2AKDM4ELMNAALDH1A1RAB9A | |
| SCHEMBL3015924 | 0.74 | KMT2A (0.57) | KMT2AKDM4ELMNAALDH1A1RAB9A | |
| SCHEMBL28162853 | 0.74 | KMT2A (0.67) | KMT2AKDM4ELMNAALDH1A1RAB9A | |
| SCHEMBL13947487 | 0.73 | ALDH1A1 (0.79) | KMT2AKDM4ELMNAALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404911-A1 | Novel processes for the preparation of piperazinyl and diazapanyl benzamide derivatives | Janssen Pharmaceutica NV (BE) | 2012-01-11 | — | — | EP | disclosed |