Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10186411 | 0.88 | ALDH1A1 (0.55) | ALDH1A1HTTKDM4ECHRM2CHRM5 | |
| SCHEMBL664132 | 0.86 | KDM4E (0.53) | ALDH1A1KDM4ECHRM2CHRM5CHRM3 | |
| SCHEMBL10186052 | 0.86 | KDM4E (0.53) | ALDH1A1KDM4ECHRM2CHRM5CHRM3 | |
| SCHEMBL664131 | 0.86 | KDM4E (0.53) | ALDH1A1KDM4ECHRM2CHRM5CHRM3 | |
| SCHEMBL663186 | 0.84 | POLB (0.49) | ALDH1A1KDM4ELMNARAB9ANPC1 | |
| SCHEMBL663187 | 0.84 | POLB (0.49) | ALDH1A1KDM4ELMNARAB9ANPC1 | |
| SCHEMBL10184988 | 0.84 | SMN1; SMN2 (0.54) | ALDH1A1RAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL10184903 | 0.84 | NPC1 (0.56) | ALDH1A1MAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL10184814 | 0.84 | NPC1 (0.56) | ALDH1A1MAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL10184804 | 0.84 | F10 (0.49) | ALDH1A1HTTKDM4EMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | ALDH1A1 963/4885HTT 922/4885KDM4E 3060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.