Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 7/20 | 0.42 |
| ▸ | HTR3A | P46098 | 3/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10186513 | 0.90 | CHRNA7 (0.42) | CHRNA7HTR3AMMP12ENPP2RXFP1 | |
| SCHEMBL10185384 | 0.88 | CHRNA7 (0.42) | CHRNA7HTR3AMMP12ENPP2DGAT1 | |
| SCHEMBL10184519 | 0.88 | CHRNA7 (0.42) | CHRNA7HTR3AMMP12DGAT1SOAT1 | |
| SCHEMBL10185037 | 0.88 | NAMPT (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10185769 | 0.87 | L3MBTL1 (0.49) | CHRNA7MMP12RXFP1DGAT1SOAT1 | |
| SCHEMBL10185749 | 0.84 | CHRNA7 (0.43) | CHRNA7HTR3AMMP12DGAT1SOAT1 | |
| SCHEMBL10186474 | 0.84 | DGAT1 (0.47) | CHRNA7HTR3AMMP12DGAT1SOAT1 | |
| SCHEMBL10186508 | 0.83 | UTS2R (0.48) | CHRNA7HTR3ADGAT1UTS2R | |
| SCHEMBL10186271 | 0.83 | UTS2R (0.42) | CHRNA7HTR3AMMP12DGAT1HDAC1 | |
| SCHEMBL10184512 | 0.82 | UTS2R (0.47) | CHRNA7HTR3AUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | CHRNA7 4193/4885HTR3A 2690/4885MMP12 1217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.