Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 7/20 | 0.49 |
| ▸ | FAAH | O00519 | 4/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.47 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10185802 | 0.88 | RAB9A (0.53) | RAB9ADGAT1DRD4FAAHEPHX2 | |
| SCHEMBL662487 | 0.85 | DGAT1 (0.56) | RAB9ADGAT1HRH3DRD2DRD3 | |
| SCHEMBL10185100 | 0.84 | DGAT1 (0.55) | RAB9ADGAT1SMYD3HRH3DRD2 | |
| SCHEMBL10185532 | 0.84 | DGAT1 (0.57) | RAB9ADGAT1HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL663532 | 0.84 | DGAT1 (0.54) | RAB9ADGAT1SMYD3HRH3DRD2 | |
| SCHEMBL662996 | 0.84 | DGAT1 (0.57) | RAB9ADGAT1HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL663533 | 0.84 | DGAT1 (0.54) | RAB9ADGAT1SMYD3HRH3DRD2 | |
| SCHEMBL662997 | 0.84 | DGAT1 (0.57) | RAB9ADGAT1HDAC3HDAC4HDAC1 | |
| SCHEMBL662093 | 0.84 | DGAT1 (0.54) | RAB9ADGAT1HRH3HDAC3HDAC4 | |
| SCHEMBL662092 | 0.84 | DGAT1 (0.54) | RAB9ADGAT1HRH3HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
| WO-2010122968-A1 | DIACYLETHYLENEDIAMINE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | RAB9A 1660/4885DGAT1 1/4885DRD4 1215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.