Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL663633 | 0.91 | DGAT1 (0.48) | ALDH1A1SMN1; SMN2DGAT1HSD17B10LMNA | |
| SCHEMBL10185794 | 0.91 | DGAT1 (0.48) | ALDH1A1SMN1; SMN2DGAT1HSD17B10LMNA | |
| SCHEMBL663632 | 0.91 | DGAT1 (0.48) | ALDH1A1SMN1; SMN2DGAT1HSD17B10LMNA | |
| SCHEMBL664557 | 0.89 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HSD17B10OPRM1OPRD1 | |
| SCHEMBL10184513 | 0.88 | DGAT1 (0.49) | ALDH1A1DGAT1HSD17B10OPRM1OPRD1 | |
| SCHEMBL664114 | 0.88 | DGAT1 (0.56) | ALDH1A1DGAT1HSD17B10OPRM1OPRD1 | |
| SCHEMBL10184323 | 0.88 | DGAT1 (0.56) | ALDH1A1DGAT1HSD17B10OPRM1OPRD1 | |
| SCHEMBL664113 | 0.88 | DGAT1 (0.56) | ALDH1A1DGAT1HSD17B10OPRM1OPRD1 | |
| SCHEMBL10185023 | 0.87 | DGAT1 (0.46) | ALDH1A1SMN1; SMN2DGAT1HSD17B10OPRM1 | |
| SCHEMBL10186137 | 0.87 | DGAT1 (0.52) | ALDH1A1SMN1; SMN2DGAT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | ALDH1A1 963/4885SMN1; SMN2 4464/4885DGAT1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.