SCHEMBL1018679

SCHEMBL1018679

O=C(c1ccccc1)C1CC(=O)N(O)C1=O.O=C1C=CC(=O)N1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.39
HTT P42858 2/20 0.36
MAPT P10636 1/20 0.36
ALOX15 P16050 1/20 0.36
HBB P68871 1/20 0.36
ALDH1A1 P00352 4/20 0.35
EP300 Q09472 1/20 0.35
LMNA P02545 1/20 0.34
PKM P14618 1/20 0.34
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
HSD17B10 Q99714 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
NPC1 O15118 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27943834 1.00 MCL1 (0.39) MCL1HTTMAPTALOX15HBB
Dimethylformamide SCHEMBL27485383 0.90 MCL1 (0.33) MCL1HTTALDH1A1LMNAPKM
SCHEMBL1934695 0.89 MCL1 (0.46) MCL1HTTMAPTALOX15HBB
Ammonia Solution, Strong SCHEMBL28851009 0.88 MCL1 (0.45) MCL1HTTMAPTALOX15HBB
SCHEMBL27451802 0.79 MCL1 (0.39) MCL1HTTMAPTALOX15HBB
SCHEMBL44224 0.76 ALDH1A1 (0.45) MCL1HTTMAPTALOX15HBB
Benzoic Acid SCHEMBL27698997 0.74 DAO (0.45) ALDH1A1POLBL3MBTL1MEN1KMT2A
SCHEMBL30817647 0.73 MCL1 (0.44) MCL1HTTMAPTALOX15HBB
SCHEMBL5009138 0.72 KDM4E (0.55) MAPTALDH1A1LMNAPOLBGAA
SCHEMBL2222585 0.72 DDAH1 (0.51) HTTALDH1A1LMNAPKMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102666879-A Templated nanoconjugates UNIV NORTHWESTERN 2012-09-12 CN claimed
EP-1704167-B1 A METHOD TO MAKE A PEPTIDE-CARRIER CONJUGATE WITH A HIGH IMMUNOGENICITY ANGELETTI P IST RICHERCHE BIO (IT) 2011-01-12 EP claimed
EP-0366770-B1 LIPOSOMES COUPLED TO HORMONES VESTAR INC (US) 1994-02-09 EP claimed
CN-116762002-A Sensor for unbiased proteome studies, methods of making and using the same 纳米马赛克公司 2023-09-15 CN disclosed
CN-110506055-A Engineered TfR combination polypeptide DENALI THERAPEUTICS INC 2019-11-26 CN disclosed
CN-110506054-A Engineered polypeptide DENALI THERAPEUTICS INC 2019-11-26 CN disclosed
EP-3058954-A2 IMMUNOGENIC COMPOSITIONS AND METHODS Longhorn Vaccines and Diagnostics, LLC (US) 2016-08-24 EP disclosed
CN-103596985-B Human monoclonal antibodies specific for glypican 3 and uses thereof 美国政府(由卫生和人类服务部的部长所代表) 2016-06-08 CN disclosed
EP-2417457-B1 PROTEIN-BASED METHODS AND COMPOSITIONS FOR THE DIAGNOSIS OF COLORECTAL ADENOCARCINOMA VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIËNTENZORG (NL) 2015-05-13 EP disclosed
CN-102781960-B HSA-related compositions and methods of use MEDIMMUNE LLC 2014-12-10 CN disclosed
CN-101802211-B Anti-normal T cell expression and secretion activating regulatory factor (RANTES) antibodies and methods of use thereof NOVIMMUNE S.A. (CH) 2014-10-01 CN disclosed
CN-1317343-A Pharmaceutical Application of mammal cell kinetin synthetic inhibitory factor SCHERING CORP (US) 2001-10-17 CN disclosed
CN-1317569-A Method for preparing mammal cell kinetin synthesis inhibiting factor SCHERING CORP (US) 2001-10-17 CN disclosed
CN-1295579-A Therapeutic uses of keratinocyte growth factor-2 HUMAN GENOME SCIENCES INC (US) 2001-05-16 CN disclosed
EP-1064375-A2 HUMAN CALCIUM-BINDING PROTEINS Incyte Pharmaceuticals, Inc. (US) 2001-01-03 EP disclosed
EP-1056869-A2 CELL CYCLE RELATED PROTEINS INCYTE PHARMACEUTICALS, INC. (US) 2000-12-06 EP disclosed
CN-1233187-A HIVp-17 peptide fragments, compositions containing the same, and methods of making and using the same VIRAL TECHNOLOGIES INC (US) 1999-10-27 CN disclosed
WO-1999049038-A2 HUMAN CALCIUM-BINDING PROTEINS INCYTE PHARMACEUTICALS, INC. (US) 1999-09-30 WO disclosed
WO-1999043829-A2 CELL CYCLE RELATED PROTEINS INCYTE PHARMACEUTICALS, INC. (US) 1999-09-02 WO disclosed
CN-1051393-A Cytokine synthesis inhibitory factor, antagonists thereof and methods of use thereof SCHERING CORP (US) 1991-05-15 CN disclosed