SCHEMBL2222585

SCHEMBL2222585

O=C(c1ccc(N2C(=O)C=CC2=O)cc1)C1CC(=O)N(O)C1=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDAH1 O94760 1/20 0.51
MGLL Q99685 11/20 0.46
FAAH O00519 5/20 0.46
HSP90AA1 P07900 3/20 0.43
TDP1 Q9NUW8 3/20 0.43
ALDH1A1 P00352 3/20 0.43
NPSR1 Q6W5P4 2/20 0.43
CACNA1B Q00975 2/20 0.43
APBA1 Q02410 2/20 0.43
HPGD P15428 2/20 0.43
PKM P14618 1/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
ADAM17 P78536 1/20 0.41
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA9 Q16790 2/20 0.39
LMNA P02545 1/20 0.39
CCR6 P51684 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL229803 0.83 MGLL (0.47) MGLLFAAHHSP90AA1TDP1ALDH1A1
SCHEMBL1934695 0.77 MCL1 (0.46) ALDH1A1HPGDPKMHTTLMNA
Ammonia Solution, Strong SCHEMBL28851009 0.76 MCL1 (0.45) ALDH1A1HPGDPKMHTTLMNA
SCHEMBL476484 0.75 TLR9 (0.49) MGLLFAAHHSP90AA1TDP1ALDH1A1
SCHEMBL25222248 0.74 ALDH1A1 (0.53) MGLLALDH1A1HPGDMAPK1ADAM17
SCHEMBL1018679 0.72 MCL1 (0.39) ALDH1A1PKMHTTLMNAL3MBTL1
SCHEMBL331470 0.70 DDAH1 (0.73) DDAH1MGLLFAAHHSP90AA1TDP1
SCHEMBL235166 0.69 DDAH1 (1.00) DDAH1MGLLFAAHHSP90AA1TDP1
SCHEMBL7591474 0.69 MGLL (0.49) DDAH1MGLLFAAHHSP90AA1TDP1
SCHEMBL22895608 0.68 HPGD (0.63) DDAH1MGLLFAAHHSP90AA1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2478049-B1 A POLYMER SUPPORT UNIV CAPE TOWN (ZA) 2015-02-25 EP claimed
US-8420802-B2 Polymer support UNIVERSITY OF CAPE TOWN (ZA) 2013-04-16 US claimed
EP-2478049-A1 A POLYMER SUPPORT University of Cape Town (ZA) 2012-07-25 EP claimed
US-20120178916-A1 Polymer Support UNIVERSITY OF CAPE TOWN (ZA) 2012-07-12 US claimed
WO-2011083360-A1 A POLYMER SUPPORT UNIVERSITY OF CAPE TOWN (ZA) 2011-07-14 WO claimed
EP-4717706-A1 MODIFIED RECOMBINANT ADENO-ASSOCIATED VIRUS (AAV)-BINDING PROTEIN AND METHOD FOR PURIFYING AAV Tosoh Corporation (JP) 2026-04-01 EP disclosed
EP-4703372-A1 IMMUNOGLOBULIN-BINDING PROTEIN Tosoh Corporation (JP) 2026-03-04 EP disclosed
US-20250236657-A1 MODIFIED RECOMBINANT ADENO-ASSOCIATED VIRUS (AAV)-BINDING PROTEIN, AND METHOD FOR ANALYZING AAV BASED ON INFECTIVITY TOSOH CORPORATION (JP) 2025-07-24 US disclosed
WO-2025105466-A1 MODIFIED FC-BINDING PROTEIN AND METHOD FOR PRODUCING SAME 東ソー株式会社 2025-05-22 WO disclosed
US-20250002543-A1 IMMUNOGLOBULIN-BINDING PROTEIN TOSOH CORPORATION (JP) 2025-01-02 US disclosed
EP-3708667-B1 IMMUNOGLOBULIN-BINDING PROTEIN TOSOH CORP (JP) 2025-01-01 EP disclosed
WO-2024242150-A1 MODIFIED RECOMBINANT ADENO-ASSOCIATED VIRUS (AAV)-BINDING PROTEIN AND METHOD FOR PURIFYING AAV 東ソー株式会社 2024-11-28 WO disclosed
EP-4083059-A1 IMPROVED ADENO-ASSOCIATED VIRUS-BINDING PROTEIN, METHOD FOR PRODUCING SAME, AND ADENO-ASSOCIATED VIRUS ADSORBENT USING SAME Tosoh Corporation (JP) 2022-11-02 EP disclosed
US-11427828-B2 Stable Fc binding protein, method for producing said protein, and antibody adsorbent in which said protein is used TOSOH CORPORATION (JP) 2022-08-30 US disclosed
US-9242010-B2 Living copolymer-protein/peptide hybrids for biomedical applications RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2016-01-26 US disclosed
EP-2478049-B1 A POLYMER SUPPORT UNIV CAPE TOWN (ZA) 2015-02-25 EP disclosed
US-8420802-B2 Polymer support UNIVERSITY OF CAPE TOWN (ZA) 2013-04-16 US disclosed
EP-2478049-A1 A POLYMER SUPPORT University of Cape Town (ZA) 2012-07-25 EP disclosed
US-20120178916-A1 Polymer Support UNIVERSITY OF CAPE TOWN (ZA) 2012-07-12 US disclosed
WO-2011083360-A1 A POLYMER SUPPORT UNIVERSITY OF CAPE TOWN (ZA) 2011-07-14 WO disclosed