Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 5/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 4/20 | 0.31 |
| ▸ | PAK1 | Q13153 | 4/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | CCNK | O75909 | 1/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | CDK7 | P50613 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.30 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20000500 | 0.75 | ALDH1A1 (0.40) | — | |
| SCHEMBL10187348 | 0.73 | ACACB (0.41) | NPY5RACACBPDE10APAK4PAK1 | |
| SCHEMBL20772888 | 0.70 | DAO (0.36) | NPY5RACACBPDE10ADAOBRD4 | |
| SCHEMBL12888681 | 0.69 | GRIN2B (0.47) | NPY5RACACBPDE10APAK4PAK1 | |
| SCHEMBL30018737 | 0.67 | ACACB (0.41) | NPY5RACACBPDE10APAK4PAK1 | |
| SCHEMBL13530424 | 0.67 | DCK (0.48) | — | |
| SCHEMBL10187135 | 0.66 | NUDT1 (0.42) | DAOBRD4CSF1R | |
| SCHEMBL13593630 | 0.64 | BRD4 (0.43) | NPY5RACACBDAOBRD4CSF1R | |
| SCHEMBL2388378 | 0.63 | BRD4 (0.51) | NPY5RPAK4PAK1AURKABRD4 | |
| SCHEMBL2388381 | 0.63 | BRD4 (0.51) | NPY5RPAK4PAK1AURKABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |