Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.51 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.38 |
| ▸ | RNASEL | Q05823 | 4/20 | 0.37 |
| ▸ | POLG | P54098 | 2/20 | 0.37 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10149537 | 0.84 | POLRMT (0.56) | POLRMTP2RX3P2RX1P2RX4P2RX2 | |
| SCHEMBL15682895 | 0.82 | POLRMT (0.55) | POLRMTP2RX3P2RX1P2RX4P2RX2 | |
| SCHEMBL24340456 | 0.81 | POLRMT (0.53) | POLRMTP2RX3P2RX1P2RX4P2RX2 | |
| SCHEMBL23047607 | 0.81 | POLRMT (0.53) | POLRMTP2RX3P2RX1P2RX4P2RX2 | |
| SCHEMBL20059049 | 0.81 | POLRMT (0.55) | POLRMTP2RX3P2RX1P2RX4P2RX2 | |
| SCHEMBL3699139 | 0.81 | POLRMT (0.55) | POLRMTP2RX3P2RX1P2RX4P2RX2 | |
| SCHEMBL13519829 | 0.81 | POLRMT (0.55) | POLRMTP2RX3P2RX1P2RX4P2RX2 | |
| SCHEMBL16710862 | 0.81 | POLRMT (0.55) | POLRMTP2RX3P2RX1P2RX4P2RX2 | |
| SCHEMBL16480932 | 0.80 | POLRMT (0.54) | POLRMTP2RX3P2RX1P2RX4P2RX2 | |
| SCHEMBL23960110 | 0.80 | POLRMT (0.57) | POLRMTP2RX3P2RX1P2RX4P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012039791-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-03-29 | — | — | WO | disclosed |