Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.55 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 6/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | POLG | P54098 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24700209 | 0.94 | POLRMT (0.48) | POLRMTP2RX3P2RX1P2RX2P2RX4 | |
| SCHEMBL23960110 | 0.90 | POLRMT (0.57) | POLRMTP2RX3P2RX1P2RX2P2RX4 | |
| SCHEMBL24699951 | 0.87 | P2RX3 (0.41) | POLRMTP2RX3P2RX1P2RX2P2RX4 | |
| SCHEMBL24340456 | 0.83 | POLRMT (0.53) | POLRMTP2RX3P2RX1P2RX2P2RX4 | |
| SCHEMBL23047607 | 0.83 | POLRMT (0.53) | POLRMTP2RX3P2RX1P2RX2P2RX4 | |
| SCHEMBL10153839 | 0.81 | POLRMT (0.61) | POLRMTP2RX3P2RX1P2RX2P2RX4 | |
| SCHEMBL10187239 | 0.81 | POLRMT (0.51) | POLRMTP2RX3P2RX1P2RX2P2RX4 | |
| SCHEMBL24340455 | 0.81 | POLRMT (0.50) | POLRMTP2RX3P2RX1P2RX2P2RX4 | |
| SCHEMBL23960108 | 0.81 | POLRMT (0.47) | POLRMTRNASELP2RY1P2RY2SRC | |
| SCHEMBL25915354 | 0.79 | DOT1L (0.36) | POLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906579-B1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC (US) | 2018-04-18 | — | — | EP | disclosed |