Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22165383 | 0.80 | KDM4E (0.42) | ALDH1A1NPC1MAPK1RAB9ATSHR | |
| SCHEMBL2955940 | 0.80 | ALDH1A1 (0.42) | ALDH1A1NPC1MAPK1RAB9ATLR8 | |
| SCHEMBL9931250 | 0.78 | HPGD (0.43) | ALDH1A1NPC1MAPK1RAB9ABTK | |
| SCHEMBL16783076 | 0.78 | BTK (0.37) | ALDH1A1NPC1MAPK1RAB9ABTK | |
| SCHEMBL509468 | 0.78 | NNMT (0.39) | ALDH1A1NPC1RAB9ATLR8TDP1 | |
| SCHEMBL24596246 | 0.77 | GABRA1 (0.40) | ALDH1A1NPC1MAPK1RAB9ABTK | |
| SCHEMBL17593270 | 0.77 | BTK (0.36) | ALDH1A1NPC1MAPK1RAB9ABTK | |
| SCHEMBL12520557 | 0.77 | ALDH1A1 (0.40) | ALDH1A1NPC1MAPK1RAB9ATLR8 | |
| SCHEMBL15908313 | 0.77 | MAPT (0.40) | ALDH1A1NPC1MAPK1RAB9ABTK | |
| SCHEMBL26927371 | 0.77 | ALDH1A1 (0.39) | ALDH1A1NPC1MAPK1RAB9ATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |