Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | MMP16 | P51512 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531023 | 0.87 | KMT2A (0.43) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL16703428 | 0.85 | CTNNB1 (0.43) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL10187775 | 0.68 | HDAC6 (0.44) | HDAC8TDP1KDM4E | |
| SCHEMBL6168541 | 0.64 | NOTUM (0.45) | ALDH1A1TSHRGAAPOLBKDM4E | |
| SCHEMBL974435 | 0.64 | CA12 (0.57) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL25060908 | 0.64 | HDAC8 (0.57) | KMT2AMEN1GAAMMP2MMP13 | |
| SCHEMBL974852 | 0.64 | CTNNB1 (0.62) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL2611428 | 0.63 | TSHR (0.45) | KMT2AMEN1TSHRGAAHDAC8 | |
| SCHEMBL25778552 | 0.62 | L3MBTL1 (0.51) | ALDH1A1TSHRGAAPOLBTDP1 | |
| SCHEMBL25778550 | 0.62 | KDM4E (0.66) | ALDH1A1TSHRGAAPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473501-A1 | COMPOUNDS AS TYROSINE KINASE MODULATORS | Allergan, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |