Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651666 | 0.87 | LMNA (0.45) | TDP1TSHRALDH1A1CYP3A4MAPT | |
| SCHEMBL30713022 | 0.85 | TDP1 (0.43) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL10621067 | 0.85 | TDP1 (0.43) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL23584099 | 0.84 | TDP1 (0.48) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL13657967 | 0.84 | GPR88 (0.40) | MCHR1NPC1RAB9ASMN1; SMN2SIGMAR1 | |
| SCHEMBL6371042 | 0.83 | TDP1 (0.50) | TDP1TSHRMCHR1MAPK1ALDH1A1 | |
| SCHEMBL746308 | 0.83 | TDP1 (0.50) | TDP1TSHRMCHR1MAPK1ALDH1A1 | |
| SCHEMBL11338351 | 0.82 | TAAR1 (0.52) | CYP1A2 | |
| SCHEMBL20367612 | 0.82 | TDP1 (0.43) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL4948726 | 0.82 | TDP1 (0.48) | TDP1TSHRMAPK1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |