Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
| ▸ | DRD5 | P21918 | 5/20 | 0.48 |
| ▸ | DRD3 | P35462 | 5/20 | 0.48 |
| ▸ | DRD1 | P21728 | 4/20 | 0.48 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.47 |
| ▸ | HTR1D | P28221 | 3/20 | 0.47 |
| ▸ | HTR1B | P28222 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | HTR2B | P41595 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10188368 | 0.86 | MAOA (0.53) | MAOAMAOBKDM4EMAPTDRD2 | |
| SCHEMBL5275095 | 0.84 | KDM4E (0.56) | MAOAMAOBKDM4EMAPTSIGMAR1 | |
| SCHEMBL29481017 | 0.73 | ALDH1A1 (0.50) | KDM4EMAPTCYP1A2SLC6A2 | |
| SCHEMBL54652 | 0.73 | ALDH1A1 (0.50) | KDM4EMAPTCYP1A2SLC6A2 | |
| SCHEMBL29391320 | 0.72 | DRD1 (0.85) | MAOAMAOBDRD2DRD5DRD3 | |
| SCHEMBL164206 | 0.72 | DRD1 (0.85) | MAOAMAOBDRD2DRD5DRD3 | |
| SCHEMBL98108 | 0.71 | MAOA (1.00) | MAOAMAOBDRD2DRD5DRD3 | |
| SCHEMBL29390912 | 0.71 | MAOA (1.00) | MAOAMAOBDRD2DRD5DRD3 | |
| SCHEMBL10188369 | 0.71 | MAOA (0.67) | MAOAMAOBDRD2DRD5DRD3 | |
| Iodide SCHEMBL28732075 | 0.70 | HRH4 (0.38) | MAOAMAOBDRD2DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242471-B1 | SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-02-29 | — | — | EP | disclosed |