Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 14/20 | 0.85 |
| ▸ | DRD5 | P21918 | 13/20 | 0.85 |
| ▸ | DRD2 | P14416 | 12/20 | 0.85 |
| ▸ | DRD3 | P35462 | 11/20 | 0.85 |
| ▸ | DRD4 | P21917 | 9/20 | 0.85 |
| ▸ | MAOA | P21397 | 2/20 | 0.85 |
| ▸ | MAOB | P27338 | 2/20 | 0.85 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL164206 | 1.00 | DRD1 (0.85) | DRD1DRD5DRD2DRD3DRD4 | |
| Iodide SCHEMBL12468173 | 0.97 | DRD1 (0.81) | DRD1DRD5DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL165521 | 0.97 | MAOA (0.86) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL29390912 | 0.92 | MAOA (1.00) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL98108 | 0.92 | MAOA (1.00) | DRD1DRD5DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL23501375 | 0.90 | MAOA (1.00) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL7973918 | 0.90 | DRD1 (0.71) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL4320673 | 0.88 | MAOA (0.91) | DRD1DRD5DRD2DRD3DRD4 | |
| Sulfuric Acid SCHEMBL174314 | 0.86 | DRD1 (0.65) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL28072797 | 0.84 | MAOA (0.83) | DRD1DRD5DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250080-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LTD (GB) | 2023-08-10 | — | — | US | disclosed |
| US-11613527-B2 | Enzyme inhibitors | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2023-03-28 | — | — | US | disclosed |
| US-20220048894-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250080-A1 | ENZYME INHIBITORS | SERPINB1, KLKB1, SERPINE1 | DRD1 4401/4885DRD5 3837/4885DRD2 4189/4885 |
| US-11613527-B2 | Enzyme inhibitors | SERPINB1, KLKB1, SERPINE1 | DRD1 4401/4885DRD5 3837/4885DRD2 4189/4885 |
| US-20220048894-A1 | ENZYME INHIBITORS | SERPINB1, KLKB1, SERPINE1 | DRD1 4401/4885DRD5 3837/4885DRD2 4189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.