SCHEMBL1019013

SCHEMBL1019013

C=C(C)C(=O)NCC(O)CO

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.46
LMNA P02545 2/20 0.41
CYP2C19 P33261 1/20 0.41
HIF1A Q16665 1/20 0.41
EGFR P00533 1/20 0.33
SRC P12931 1/20 0.33
ALDH1A1 P00352 3/20 0.32
DRD3 P35462 1/20 0.31
SLC6A3 Q01959 1/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3738357 0.89 TGFBR1 (0.41) TGFBR1LMNACYP2C19HIF1AALDH1A1
SCHEMBL9336802 0.85 TGFBR1 (0.42) TGFBR1LMNACYP2C19HIF1AKDM4E
SCHEMBL28346307 0.84 TGFBR1 (0.39) TGFBR1LMNACYP2C19HIF1A
SCHEMBL14931 0.83 TGFBR1 (0.37) TGFBR1LMNAALDH1A1RXFP1
SCHEMBL15374908 0.83 LMNA (0.43) TGFBR1LMNACYP2C19HIF1AEGFR
SCHEMBL15374912 0.83 LMNA (0.43) TGFBR1LMNACYP2C19HIF1AEGFR
SCHEMBL15374906 0.83 LMNA (0.43) TGFBR1LMNACYP2C19HIF1AEGFR
SCHEMBL25763048 0.82 ALDH1A1 (0.42) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL8672834 0.82 TGFBR1 (0.36) TGFBR1LMNAKDM4ERXFP1
SCHEMBL9818639 0.82 TGFBR1 (0.36) TGFBR1RXFP1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3655446-B1 WATER-SOLUBLE, THERMALLY-CROSSLINKABLE POLYMERIC MATERIAL COMPRISING ONE OR MORE POLY(METH)ACRYLAMIDE-BASED COPOLYMERS WITH CARBOXYL-TERMINATED PENDANT CHAINS ALCON INC (CH) 2022-08-31 EP claimed
EP-2794727-B2 IONIC SILICONE HYDROGELS JOHNSON & JOHNSON VISION CARE (US) 2020-10-28 EP claimed
EP-2794723-B9 SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS JOHNSON & JOHNSON VISION CARE (US) 2019-11-20 EP claimed
EP-2794723-B1 SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS JOHNSON & JOHNSON VISION CARE (US) 2019-04-24 EP claimed
EP-2794725-B1 SILICONE HYDROGELS COMPRISING N-VINYL AMIDES AND HYDROXYALKYL (METH)ACRYLATES OR (METH)ACRYLAMIDES JOHNSON & JOHNSON VISION CARE (US) 2018-07-11 EP claimed
EP-2794727-B1 IONIC SILICONE HYDROGELS JOHNSON & JOHNSON VISION CARE (US) 2018-01-24 EP claimed
EP-2794726-B1 SILICONE HYDROGELS COMPRISING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY JOHNSON & JOHNSON VISION CARE (US) 2016-10-26 EP claimed
US-9140825-B2 Ionic silicone hydrogels JOHNSON & JOHNSON VISION CARE, INC. (US) 2015-09-22 US claimed
US-20140031447-A1 SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS JOHNSON & JOHNSON VISION CARE, INC. (US) 2014-01-30 US claimed
US-20140031449-A1 SILICONE HYDROGELS FORMED FROM ZERO DILUENT REACTIVE MIXTURES JOHNSON & JOHNSON VISION CARE, INC. (US) 2014-01-30 US claimed
US-20130317131-A1 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-11-28 US claimed
US-20130168617-A1 IONIC SILICONE HYDROGELS JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-07-04 US claimed
US-8329845-B2 Divided redox-curing type composition KURARAY NORITAKE DENTAL INC. (JP) 2012-12-11 US claimed
US-7498699-B2 Electret and composite formed therewith INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2009-03-03 US claimed
US-20050107555-A1 copolymers of Vinylidene fluoride with either Hexafluoropropylene, Chlorotetrafluoroethylene, or Tetrafluoroethylene; better charge stability, adhesion with a substrate, processability, and solubility VERISONIX CORPORATION (TW) 2005-05-19 US claimed
EP-0596023-B1 PAINT COMPOSITION HEMPELS SKIBSFARVE FAB J C (DK) 1998-10-14 EP claimed
US-5232981-A Dispersion polymers, a process for the preparation thereof, and the use thereof BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1993-08-03 US claimed
EP-0227054-B1 DISPERSION POLYMERS, PROCESS FOR THEIR PREPARATION AND THEIR USE BEHRINGWERKE Aktiengesellschaft (DE) 1991-09-18 EP claimed
US-4945146-A Dispersion polymers processes for their preparation and their use BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1990-07-31 US claimed
EP-0227054-A2 Dispersion polymers, process for their preparation and their use BEHRINGWERKE Aktiengesellschaft (DE) 1987-07-01 EP claimed