Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24717530 | 0.98 | LTA4H (0.33) | LTA4HL3MBTL3L3MBTL1HTR6 | |
| SCHEMBL24718638 | 0.98 | LTA4H (0.33) | LTA4HL3MBTL3L3MBTL1HTR6 | |
| SCHEMBL22969970 | 0.84 | MEN1 (0.36) | L3MBTL3L3MBTL1HTR6 | |
| SCHEMBL10191535 | 0.81 | KDM4E (0.34) | — | |
| SCHEMBL22912561 | 0.81 | HTR6 (0.38) | HTR6 | |
| SCHEMBL8379545 | 0.79 | CYP2A13 (0.38) | L3MBTL3L3MBTL1 | |
| SCHEMBL17489227 | 0.79 | HTR6 (0.36) | HTR6 | |
| SCHEMBL12465280 | 0.78 | MEN1 (0.44) | L3MBTL3L3MBTL1HTR6 | |
| SCHEMBL10863172 | 0.78 | OPRM1 (0.33) | HTR6 | |
| SCHEMBL21573201 | 0.76 | MEN1 (0.43) | L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735386-B2 | Aminopyrazoloquinazolines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-27 | — | — | US | disclosed |
| WO-2012010704-A1 | NEW AMINOPYRAZOLOQUINAZOLINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-26 | — | — | WO | disclosed |