Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREB1 | P16220 | 6/20 | 0.73 |
| ▸ | BCHE | P06276 | 2/20 | 0.61 |
| ▸ | ACHE | P22303 | 2/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TNKS | O95271 | 3/20 | 0.53 |
| ▸ | GABRP | O00591 | 2/20 | 0.53 |
| ▸ | GABRD | O14764 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL972006 | 0.94 | CREB1 (0.83) | CREB1BCHEACHEABCB1MAPT | |
| SCHEMBL21335353 | 0.86 | CREB1 (0.74) | CREB1BCHEACHEABCB1MAPT | |
| SCHEMBL30852784 | 0.86 | CREB1 (0.77) | CREB1BCHEACHEABCB1MAPT | |
| SCHEMBL27797164 | 0.86 | CREB1 (0.76) | CREB1BCHEACHEABCB1MAPT | |
| SCHEMBL971995 | 0.85 | CREB1 (1.00) | CREB1BCHEACHEABCB1MAPT | |
| SCHEMBL971866 | 0.84 | CREB1 (0.73) | CREB1BCHEACHEABCB1MAPT | |
| SCHEMBL2398442 | 0.81 | HPGD (0.54) | CREB1BCHEACHEABCB1MAPT | |
| SCHEMBL969833 | 0.81 | ABCB1 (0.71) | CREB1BCHEACHEABCB1MAPT | |
| SCHEMBL21515195 | 0.81 | L3MBTL1 (0.69) | CREB1BCHEACHEABCB1MAPT | |
| SCHEMBL30852834 | 0.81 | ABCB1 (0.65) | CREB1BCHEACHEABCB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7875650-B2 | Baicalein analogs; enhances bioavailability of active compounds, especially orally administered compounds, by inhibition of P-glycoprotein 170 (P-gp 170) and/or CYP450 enzyme; 6-Acetoxy-5,7-dihydroxyflavone | YALE UNIVERSITY (US) | 2011-01-25 | — | — | US | disclosed |