Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.52 |
| ▸ | RELA | Q04206 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.51 |
| ▸ | APP | P05067 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679343 | 1.00 | NPC1 (0.52) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL22171107 | 0.97 | ABCG2 (0.54) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL19193810 | 0.93 | CYP1A1 (0.53) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL19193677 | 0.92 | ABCG2 (0.43) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL15362246 | 0.92 | ABCG2 (0.43) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL15315057 | 0.92 | KDM4E (0.46) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL19193813 | 0.91 | ABCG2 (0.44) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL17014955 | 0.90 | CA12 (0.51) | ABCG2CYP3A4ESR1CYP1A1CYP1B1 | |
| SCHEMBL3633038 | 0.89 | ABCG2 (0.42) | NPC1LMNASMN1; SMN2ABCG2CYP1A2 | |
| SCHEMBL19193697 | 0.89 | ABCG2 (0.44) | LMNASMN1; SMN2ABCG2APPESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329823-B2 | Photocrosslinkable materials | ROLIC AG (CH) | 2012-12-11 | — | — | US | disclosed |
| US-8329823-B2 | Photocrosslinkable materials | ROLIC AG (CH) | 2012-12-11 | — | — | US | disclosed |
| US-20120076952-A1 | PHOTOCROSSLINKABLE MATERIALS | ROLIC AG (CH) | 2012-03-29 | — | — | US | disclosed |
| US-20120076952-A1 | PHOTOCROSSLINKABLE MATERIALS | ROLIC AG (CH) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120076952-A1 | PHOTOCROSSLINKABLE MATERIALS | DDC, PARG, ALAD | NPC1 4864/4885LMNA 2057/4885NFKB1 3202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.