SCHEMBL1019627

SCHEMBL1019627

Cc1c(CCl)ccc(CCl)c1C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PON1 P27169 1/20 0.35
KMT2A Q03164 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2495516 0.89 PON1 (0.43) PON1KMT2ANPSR1TSHR
Ammonia Solution, Strong SCHEMBL197655 0.87 PON1 (0.38) PON1ALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL136349 0.87 PON1 (0.46) PON1TSHR
Phosphine SCHEMBL15203731 0.87 PON1 (0.42) PON1TSHR
SCHEMBL1271763 0.87 PON1 (0.31) PON1
SCHEMBL1271713 0.84 PON1 (0.30) PON1
SCHEMBL6914998 0.81 TSHR (0.38) PON1KMT2ANPSR1ALDH1A1TSHR
SCHEMBL2103383 0.81 MEN1 (0.51) KMT2AALDH1A1TSHR
SCHEMBL10785131 0.81 GABRA1 (0.35) KMT2AALDH1A1TSHR
SCHEMBL8100604 0.79 ALDH1A1 (0.35) KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2137228-B1 POLYESTER COMPOSITIONS HAVING IMPROVED HEAT RESISTANCE SABIC INNOVATIVE PLASTICS IP (NL) 2011-01-12 EP disclosed
US-20080242783-A1 POLYESTER COMPOSITIONS HAVING IMPROVED HEAT RESISTANCE CITIBANK, N.A., AS COLLATERAL AGENT 2008-10-02 US disclosed
US-20080242784-A1 POLYESTER COMPOSITIONS HAVING IMPROVED HEAT RESISTANCE CITIBANK, N.A., AS COLLATERAL AGENT 2008-10-02 US disclosed
US-20040075802-A1 Sealant for liquid crystal display cell, composition for liquid crystal display cell sealant and liquid crystal display element MITSUI CHEMICALS, INC. (JP) 2004-04-22 US disclosed
EP-1153952-A1 SEALING AGENT FOR LIQUID-CRYSTAL DISPLAY CELL, COMPOSITION FOR SEALING AGENT FOR LIQUID-CRYSTAL DISPLAY CELL, AND LIQUID-CRYSTAL DISPLAY ELEMENT Mitsui Chemicals, Inc. (JP) 2001-11-14 EP disclosed