SCHEMBL1019988

SCHEMBL1019988

c1nc2c(s1)CCNC2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL16054017 0.98 PNMT (0.44)
SCHEMBL3533710 0.88 DRD2 (0.39)
SCHEMBL3725694 0.86 DRD2 (0.38)
SCHEMBL550241 0.85 DRD2 (0.46)
SCHEMBL9500822 0.83 PNMT (0.41)
SCHEMBL397802 0.83
Hydrochloric Acid SCHEMBL550220 0.83 DRD2 (0.44)
Hydrochloric Acid SCHEMBL22395725 0.82 DRD2 (0.40)
Hydrochloric Acid SCHEMBL12485568 0.82 DRD2 (0.40)
SCHEMBL951473 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240132480-A1 INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE TRI-INSTITUTIONAL THERAPEUTICS DISCOVERY INSTITUTE, INC. 2024-04-25 US claimed
CN-111491918-B Aryl and heteroaryl substituted indole compounds 百时美施贵宝公司 2023-10-24 CN claimed
US-20220289753-A1 SHP2 INHIBITORS IRBM S.P.A. (IT) 2022-09-15 US claimed
WO-2022150574-A1 INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE CORNELL UNIVERSITY (US) 2022-07-14 WO claimed
CN-114728935-A SHP2 inhibitor IRBM股份公司 2022-07-08 CN claimed
EP-4010335-A1 SHP2 INHIBITORS IRBM S.P.A. (IT) 2022-06-15 EP claimed
WO-2021028362-A1 SHP2 INHIBITORS IRBM S.P.A. (IT) 2021-02-18 WO claimed
EP-3772513-A1 SHP2 INHIBITORS C.N.C.C.S. S.c.a.r.l. Collezione Nazionale Dei Composti Chimici e Centro Screening (IT) 2021-02-10 EP claimed
US-20100292188-A1 Compounds Comprising A Cyclobutoxy Group UCB PHARMA S.A. (BE) 2010-11-18 US claimed
EP-2238144-A1 COMPOUNDS COMPRISING A CYCLOBUTOXY GROUP UCB Pharma, S.A. (BE) 2010-10-13 EP claimed
WO-2009092764-A1 COMPOUNDS COMPRISING A CYCLOBUTOXY GROUP UCB PHARMA, S.A. (BE) 2009-07-30 WO claimed
WO-2026099510-A1 RESILIENT MARKER COMPOUNDS MINTON, TREHARNE & DAVIES LIMITED (GB) 2026-05-15 WO disclosed
WO-2026087753-A1 PROCESS FOR REDUCING A NITROGEN-CONTAINING FUNCTIONAL GROUP OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2026-04-30 WO disclosed
EP-4733294-A1 NOVEL PROCESS Oxford University Innovation Limited (GB) 2026-04-29 EP disclosed
US-20260085077-A1 HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2026-03-26 US disclosed
EP-2049548-A1 FUSED OXAZOLES &amp; THIAZOLES AS HISTAMINE H3- RECEPTOR LIGANDS UCB Pharma, S.A. (BE) 2009-04-22 EP disclosed
EP-2019094-A1 HETEROCYCLIC TYPE CINNAMIDE DERIVATIVE Eisai R&D Management Co., Ltd. (JP) 2009-01-28 EP disclosed
WO-2008012010-A1 FUSED OXAZOLES &amp; THIAZOLES AS HISTAMINE H3- RECEPTOR LIGANDS UCB PHARMA, S.A. (BE) 2008-01-31 WO disclosed
EP-1287018-A2 THROMBIN INHIBITORS Lek Pharmaceutical and Chemical Co. D.D. (SI) 2003-03-05 EP disclosed
WO-2001085760-A1 THROMBIN INHIBITORS LEK PHARMACEUTICAL & CHEMICAL CO. DD (SI) 2001-11-15 WO disclosed