Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CD44 | P16070 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397802 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL12485568 | 0.98 | DRD2 (0.40) | PNMTDRD2DRD3MAPK1PDCD1 | |
| Hydrochloric Acid SCHEMBL22395725 | 0.98 | DRD2 (0.40) | PNMTDRD2DRD3MAPK1PDCD1 | |
| SCHEMBL3725694 | 0.94 | DRD2 (0.38) | PNMTDRD2DRD3MAPK1PDCD1 | |
| Urea SCHEMBL21906543 | 0.89 | PNMT (0.40) | PNMTDRD2DRD3MAPK1APEX1 | |
| SCHEMBL3582148 | 0.88 | DRD2 (0.39) | PNMTDRD2DRD3MAPK1 | |
| SCHEMBL550241 | 0.85 | DRD2 (0.46) | PNMTDRD2DRD3MAPK1HTR2C | |
| Hydrochloric Acid SCHEMBL550220 | 0.83 | DRD2 (0.44) | PNMTDRD2DRD3MAPK1 | |
| SCHEMBL1019988 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL16054017 | 0.82 | PNMT (0.44) | PNMTDRD2DRD3MAPK1PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214051-A | Thiazolyl and oxazolyl[5,4-c]piperidyl-substituted quinolone-carboxylic acid and related analogs thereof having antibacterial properties are disclosed | PFIZER INC. (US) | 1993-05-25 | — | — | US | disclosed |