Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 7/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994922 | 0.83 | KDM4E (0.49) | KMT2ACES2CES1MAPTMGLL | |
| SCHEMBL12670979 | 0.81 | ADORA2A (0.41) | KMT2ACES2CES1MAPTMGLL | |
| SCHEMBL7994918 | 0.76 | PPARA (0.53) | PPARAALDH1A1 | |
| SCHEMBL16638710 | 0.73 | KMT2A (0.36) | KMT2ACES2CES1KRAS | |
| SCHEMBL4688589 | 0.72 | PPARA (0.48) | KMT2AKCNN4MAPTPPARAALDH1A1 | |
| SCHEMBL3861716 | 0.71 | MAPT (0.50) | KMT2AKCNN4CES2CES1MAPT | |
| SCHEMBL2822682 | 0.71 | PPARA (0.54) | KMT2AMAPTPPARAALDH1A1 | |
| SCHEMBL528652 | 0.70 | LMNA (0.43) | KMT2ACES2CES1MAPTKRAS | |
| SCHEMBL2668164 | 0.70 | GCK (0.45) | KMT2AKCNN4CES2CES1MAPT | |
| Hydrochloric Acid SCHEMBL28262394 | 0.69 | LMNA (0.43) | KMT2ACES2CES1MAPTKRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125735-B1 | 2,2,2-TRI-SUBSTITUTED ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS PRIVATE LTD (IN) | 2012-06-27 | — | — | EP | disclosed |