SCHEMBL1020071

SCHEMBL1020071

CC(=O)OC1(N)CCCC1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TSHR P16473 2/20 0.32
CYP2C19 P33261 1/20 0.32
EP300 Q09472 1/20 0.30
HIF1A Q16665 1/20 0.30
CREBBP Q92793 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4079599 0.97 ALDH1A1 (0.31) ALDH1A1SMN1; SMN2NPSR1TSHRCYP2C19
SCHEMBL2192555 0.97 TSHR (0.36) ALDH1A1SMN1; SMN2NPSR1TSHRCYP2C19
Hydrochloric Acid SCHEMBL11579187 0.95 TSHR (0.34) ALDH1A1SMN1; SMN2NPSR1TSHRCYP2C19
SCHEMBL19392125 0.95
Hydrochloric Acid SCHEMBL27994742 0.92 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL27869033 0.89
Hydrochloric Acid SCHEMBL16666609 0.86
SCHEMBL14677216 0.81
SCHEMBL28027738 0.80
SCHEMBL3164465 0.79 TSHR (0.37) TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612624-B2 Light-inducible CRISPR/Cas9 system for genome editing THE JOHNS HOPKINS UNIVERSITY (US) 2026-04-28 US disclosed
US-12404312-B2 Engineered VEGF variants for retinal neuroprotection, promotion of axon growth and axon regeneration MASSACHUSETTS EYE AND EAR INFIRMARY (US) 2025-09-02 US disclosed
US-20250250562-A1 TAT-INDUCED CRISPR/ENDONUCLEASE-BASED GENE EDITING UNIV TEMPLE (US) 2025-08-07 US disclosed
US-12377162-B2 Anti-serine protease inhibitor kazal (SPIK) antibodies, immunoconjugates, and methods of use IMCARE BIOTECH, LLC (US) 2025-08-05 US disclosed
US-12357704-B2 Tailored hypoimmune nanovesicular delivery systems for cancer tumors Malcolm, Thomas (US) 2025-07-15 US disclosed
EP-4522193-A2 METHODS FOR TREATING AND/OR PREVENTING UNDESIRABLE SEQULAE OF NASAL TURBINOPLASTY OR FUNCTIONAL ENDOSCOPIC SINUS SURGERY 3-D Matrix Ltd. (JP) 2025-03-19 EP disclosed
US-12251429-B2 Methods and compositions for RNA-guided treatment of HIV infection Temple University—Of the Commonwealth System of Higher Education (US) 2025-03-18 US disclosed
US-20250082778-A1 RNA GUIDED ERADICATION OF HUMAN JC VIRUS AND OTHER POLYOMAVIRUSES TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2025-03-13 US disclosed
WO-2025019820-A1 ALL IN ONE VECTORS FOR THE TREATMENT OF FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY NEVADA RESEARCH & INNOVATION CORPORATION (US) 2025-01-23 WO disclosed
US-20250001014-A1 BAG3 COMPOSITIONS AND METHODS TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2025-01-02 US disclosed
WO-2008134544-A1 COMPOSITIONS FOR PREVENTION OF ADHESIONS AND OTHER BARRIER APPLICATIONS ARCH THERAPEUTICS, INC. (US) 2008-11-06 WO disclosed
WO-2008113030-A2 TREATMENT OF LEAKY OR DAMAGED TIGHT JUNCTIONS AND ENHANCING EXTRACELLULAR MATRIX ARCH THERAPEUTICS, INC (US) 2008-09-18 WO disclosed
WO-2008100966-A1 GDNF-DERIVED PEPTIDES THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2008-08-21 WO disclosed
CN-101247804-A chemical compound SMITHKLINE BEECHAM CORP (US) 2008-08-20 CN disclosed
US-20080032934-A1 COMPOSITIONS FOR PREVENTION OF ADHESIONS AND OTHER BARRIER APPLICATIONS CLEAR NANO SOLUTIONS 2008-02-07 US disclosed
EP-1879606-A1 COMPOSITIONS AND METHODS FOR PROMOTING HEMOSTASIS AND OTHER PHYSIOLOGICAL ACTIVITIES Massachussets Institute of Technology (US) 2008-01-23 EP disclosed
US-20070203062-A1 Compositions and methods for promoting hemostasis and other physiological activities NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-08-30 US disclosed
WO-2006116524-A1 COMPOSITIONS AND METHODS FOR PROMOTING HEMOSTASIS AND OTHER PHYSIOLOGICAL ACTIVITIES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2006-11-02 WO disclosed
US-4217238-A BASIC SALT, SCRUBBING EXXON RESEARCH & ENGINEERING CO. (US) 1980-08-12 US disclosed
US-4094957-A CARBON DIOXIDE EXXON RESEARCH & ENGINEERING CO. (US) 1978-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612624-B2 Light-inducible CRISPR/Cas9 system for genome editing RNMT, AMPD2, NT5C2 ALDH1A1 4025/4885SMN1; SMN2 922/4885NPSR1 3044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.