Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | CCR8 | P51685 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 3/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1892669 | 0.80 | LTA4H (0.42) | LTA4HKCNH2CCR1CCR5CCR8 | |
| SCHEMBL21206677 | 0.77 | KDR (0.41) | LTA4HKCNH2HSD17B10KDM4ECCR1 | |
| SCHEMBL13322718 | 0.77 | LTA4H (0.40) | LTA4HKCNH2MAPK1AURKANOS3 | |
| SCHEMBL13322719 | 0.77 | LTA4H (0.38) | LTA4HKCNH2CCR1CCR5CCR8 | |
| SCHEMBL21206682 | 0.74 | LTA4H (0.36) | LTA4HKCNH2AURKA | |
| SCHEMBL21101382 | 0.69 | CCR1 (0.52) | KDM4ECDK4CDK2CCNE1CCR1 | |
| SCHEMBL13675199 | 0.68 | CHRM4 (0.39) | HSD17B10KDM4EMAPK1CDK4CDK2 | |
| SCHEMBL1885425 | 0.68 | CCR1 (0.37) | LTA4HKCNH2KDM4ECCR1CCR5 | |
| SCHEMBL17339834 | 0.67 | HSD17B10 (0.44) | HSD17B10KDM4EMAPK1CDK4CDK2 | |
| SCHEMBL10271448 | 0.67 | AHR (0.46) | HSD17B10KDM4EMAPK1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210070754-A1 | JAK INHIBITOR AND USE THEREOF | ZHUHAI UNITED LABORATORIES CO., LTD. (CN) | 2021-03-11 | — | — | US | disclosed |
| US-20120030841-A1 | Isoxazoline compounds for combating invertebrate pests | BASF SE (DE) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210070754-A1 | JAK INHIBITOR AND USE THEREOF | JAK1, JAK2, TYK2 | LTA4H 2196/4885KCNH2 2870/4885HSD17B10 2610/4885 |
| US-20120030841-A1 | Isoxazoline compounds for combating invertebrate pests | PRDX5, PRDX1, PRDX2 | LTA4H 2754/4885KCNH2 1054/4885HSD17B10 2405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.