Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 4/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27192249 | 0.79 | PRMT5 (0.36) | PRMT5WDR77ELANENUDT1 | |
| SCHEMBL27192312 | 0.79 | PRMT5 (0.34) | PRMT5WDR77ELANE | |
| SCHEMBL4783388 | 0.79 | PRMT5 (0.34) | PRMT5WDR77ELANE | |
| SCHEMBL31509787 | 0.79 | PRMT5 (0.36) | PRMT5WDR77ELANENUDT1 | |
| SCHEMBL4785727 | 0.79 | PRMT5 (0.34) | PRMT5WDR77ELANEGAA | |
| SCHEMBL5542790 | 0.70 | ELANE (0.56) | ELANE | |
| SCHEMBL10200866 | 0.70 | ELANE (0.39) | ELANEGAAL3MBTL1 | |
| SCHEMBL26110247 | 0.67 | NUDT1 (0.43) | ELANENUDT1GAAL3MBTL1 | |
| SCHEMBL1285134 | 0.67 | NUDT1 (0.52) | ELANENUDT1GAAL3MBTL1 | |
| SCHEMBL14437987 | 0.65 | ELANE (0.35) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120030841-A1 | Isoxazoline compounds for combating invertebrate pests | BASF SE (DE) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120030841-A1 | Isoxazoline compounds for combating invertebrate pests | PRDX5, PRDX1, PRDX2 | PRMT5 3179/4885WDR77 3507/4885ELANE 3941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.