Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 12/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371154 | 0.80 | MRGPRX4 (0.62) | MRGPRX4MAOAMAOBGCGRHPGD | |
| SCHEMBL365277 | 0.78 | MRGPRX4 (0.58) | MRGPRX4MAOAMAOBGCGRHPGD | |
| SCHEMBL367030 | 0.76 | MRGPRX4 (0.67) | MRGPRX4HPGDSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL364527 | 0.68 | SCN9A (0.63) | MRGPRX4HPGDSMN1; SMN2KMT2ASCN9A | |
| SCHEMBL9586217 | 0.68 | MRGPRX4 (0.47) | MRGPRX4MAOAMAOBPPARA | |
| SCHEMBL364759 | 0.65 | MRGPRX4 (0.64) | MRGPRX4HPGDSMN1; SMN2KMT2ASCN9A | |
| SCHEMBL30792326 | 0.65 | MRGPRX4 (0.46) | MRGPRX4MAOAMAOBSCN9ANPC1 | |
| SCHEMBL364950 | 0.64 | MAOB (0.66) | MRGPRX4MAOAMAOBSMN1; SMN2SCN9A | |
| SCHEMBL4268320 | 0.63 | MAPT (0.58) | MRGPRX4HPGDSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL2561786 | 0.62 | ENPP2 (0.57) | MRGPRX4HPGDSMN1; SMN2KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007868-A2 | CHEMICAL COMPOUNDS | PFIZER LIMITED (GB) | 2012-01-19 | — | — | WO | disclosed |