Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT2 | P23786 | 2/20 | 0.38 |
| ▸ | CPT1A | P50416 | 2/20 | 0.38 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 4/20 | 0.35 |
| ▸ | SKP1 | P63208 | 4/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL622833 | 0.75 | LOXL2 (0.43) | CHRM4LOXL2 | |
| SCHEMBL623692 | 0.75 | HRH4 (0.47) | HRH4KDM4EHSD17B10LOXL2LRRK2 | |
| SCHEMBL623270 | 0.75 | CYP1A2 (0.48) | HRH4 | |
| SCHEMBL622712 | 0.75 | HPGD (0.49) | CHRM4LRRK2CHRM2CHRM5CHRM1 | |
| SCHEMBL624199 | 0.75 | CYP1A2 (0.48) | HRH4KDM4ELOXL2 | |
| SCHEMBL15025401 | 0.75 | RET (0.46) | KDM4E | |
| SCHEMBL624464 | 0.75 | KMT2A (0.54) | CPT2CPT1ACPT1BKDM4E | |
| SCHEMBL624235 | 0.75 | RET (0.46) | KDM4E | |
| SCHEMBL624236 | 0.75 | RET (0.46) | KDM4E | |
| SCHEMBL624208 | 0.74 | SCD5 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020567-A1 | ACYL PIPERAZINE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-02-16 | — | — | WO | disclosed |