SCHEMBL622833

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15006743	0.83	KMT2A (0.50)	SMN1; SMN2NPC1ALDH1A1ATMKMT2A
	SCHEMBL15006772	0.82	LOXL2 (0.38)	LOXL2SMN1; SMN2ALDH1A1MEN1KMT2A
	SCHEMBL624464	0.82	KMT2A (0.54)	SMN1; SMN2ALDH1A1MEN1KMT2A
	SCHEMBL15025401	0.82	RET (0.46)	ALDH1A1
	SCHEMBL624236	0.82	RET (0.46)	ALDH1A1
	SCHEMBL624235	0.82	RET (0.46)	ALDH1A1
	SCHEMBL623225	0.81	RET (0.43)	LOXL2SMN1; SMN2FAAH
	SCHEMBL622875	0.81	HSD17B10 (0.53)	LOXL2ALDH1A1CHRM4MEN1KMT2A
	SCHEMBL623675	0.81	ROCK2 (0.45)	LOXL2ALDH1A1
	SCHEMBL623261	0.81	RET (0.43)	LOXL2SMN1; SMN2FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.