Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.30 |
| ▸ | CHRNB3 | Q05901 | 4/20 | 0.30 |
| ▸ | CHRNA6 | Q15825 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14651113 | 0.76 | ALDH1A1 (0.32) | — | |
| SCHEMBL10202903 | 0.71 | — | — | |
| SCHEMBL10202926 | 0.71 | — | — | |
| SCHEMBL10202914 | 0.71 | — | — | |
| SCHEMBL12050301 | 0.71 | — | — | |
| SCHEMBL15760350 | 0.70 | — | — | |
| SCHEMBL10202916 | 0.69 | — | — | |
| SCHEMBL10202913 | 0.67 | — | — | |
| SCHEMBL10441953 | 0.66 | GABRR1 (0.48) | GABRR1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL7722913 | 0.66 | GABRR1 (0.48) | GABRR1CHRNB2CHRNA3CHRNA4CHRNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035214-A1 | RENIN INHIBITORS | MERCK CANADA INC. (CA) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035214-A1 | RENIN INHIBITORS | REN, ACE, AGTR1 | GABRR1 923/4885CHRNB2 4697/4885CHRNA3 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.