Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 16/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623745 | 0.76 | HPGD (0.53) | ACACBCHRM4CHRM2CHRM5CHRM1 | |
| SCHEMBL624105 | 0.74 | ACACB (0.41) | ACACBCHRM4KDM4E | |
| SCHEMBL623302 | 0.72 | GPR119 (0.54) | ACACB | |
| SCHEMBL623285 | 0.71 | ACACB (0.45) | ACACBCHRM4CHRM2CHRM5CHRM1 | |
| SCHEMBL623906 | 0.70 | PTK2 (0.54) | ACACBCHRM4 | |
| SCHEMBL623587 | 0.70 | L3MBTL1 (0.48) | ACACBCHRM4KDM4EHRH3 | |
| SCHEMBL623193 | 0.70 | ALDH1A1 (0.61) | ACACBCHRM4CHRM2CHRM5CHRM1 | |
| SCHEMBL622338 | 0.69 | ACACB (0.43) | ACACBCHRM4CHRM2CHRM5CHRM1 | |
| SCHEMBL623169 | 0.69 | TSHR (0.53) | ACACBKDM4EHRH3 | |
| SCHEMBL624559 | 0.69 | GRM5 (0.59) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020567-A1 | ACYL PIPERAZINE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-02-16 | — | — | WO | disclosed |