SCHEMBL1020543

SCHEMBL1020543

CCCCCCc1ccc(C(=O)Cl)cc1

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRA P10827 9/20 0.70
THRB P10828 9/20 0.70
RARB P10826 5/20 0.65
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
ALDH1A1 P00352 1/20 0.65
RARA P10276 1/20 0.65
MAPT P10636 1/20 0.65
MTOR P42345 1/20 0.65
PLA2G1B P04054 3/20 0.59
ATG4B Q9Y4P1 3/20 0.59
CYP1A2 P05177 1/20 0.59
TDP1 Q9NUW8 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2385561 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL269399 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL1021538 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL8960387 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL8728345 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL1021352 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL9431010 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL17272985 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL2180222 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL158152 0.98 THRA (0.67) THRATHRBRARBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109574842-B Vegetable oil polyalcohol and preparation method and application thereof 南京工业大学 2020-05-05 CN claimed
EP-0025119-B1 NEMATIC CRYSTALLINE-LIQUID 5-ALKYL-2-(4-ACYLOXYPHENYL)-PYRIMIDINES FOR OPTO-ELECTRONIC ARRANGEMENTS AND PROCESS FOR THEIR PREPARATION VEB Werk Für Fernsehelektronik im VEB Kombinat Mikroelektronik (DD) 1983-05-25 EP claimed
EP-0025119-A1 Nematic crystalline-liquid 5-alkyl-2-(4-acyloxyphenyl)-pyrimidines for opto-electronic arrangements and process for their preparation VEB Werk Für Fernsehelektronik im VEB Kombinat Mikroelektronik (DD) 1981-03-18 EP claimed
CN-118027395-B Coating material, preparation method and application thereof, and lithium battery diaphragm 安徽壹石通材料科学研究院有限公司 2025-04-29 CN disclosed
CN-118027395-A Coating material, preparation method and application thereof, and lithium battery diaphragm 安徽壹石通材料科学研究院有限公司 2024-05-14 CN disclosed
CN-115677721-B Benzotriazine free radical compound, preparation method thereof and application thereof in organic memory 郑州大学 2023-11-24 CN disclosed
US-11795058-B2 Silicon dioxide composite particle with far-infrared radioactivity; precursor of the same and application thereof NATIONAL CHI NAN UNIVERSITY (TW) 2023-10-24 US disclosed
CN-115677721-A Benzotriazine free radical compound, preparation method thereof and application thereof in organic memory 郑州大学 2023-02-03 CN disclosed
CN-111171174-B Glucan derivatives, process for their preparation and agents for their use in the preparation of medicaments 上海图珐医药科技有限公司 2022-02-01 CN disclosed
WO-2021143939-A1 GLUCAN DERIVATIVE AND PREPARATION METHOD THEREFOR, AND ADDITIVE USED FOR PREPARING MEDICINE 上海图珐医药科技有限公司 2021-07-22 WO disclosed
EP-1639058-B1 PHOTOCHROMIC COMPOUNDS TRANSITIONS OPTICAL INC (US) 2020-10-21 EP disclosed
US-4481149-A LIQUID CRYSTALS DAIKIN KOGYO CO., LTD. (JP) 1984-11-06 US disclosed
US-4393231-A LIQUID CRYSTALS DAIKIN KOGYO CO., LTD. (JP) 1983-07-12 US disclosed
EP-0025119-B1 NEMATIC CRYSTALLINE-LIQUID 5-ALKYL-2-(4-ACYLOXYPHENYL)-PYRIMIDINES FOR OPTO-ELECTRONIC ARRANGEMENTS AND PROCESS FOR THEIR PREPARATION VEB Werk Für Fernsehelektronik im VEB Kombinat Mikroelektronik (DD) 1983-05-25 EP disclosed
EP-0025119-A1 Nematic crystalline-liquid 5-alkyl-2-(4-acyloxyphenyl)-pyrimidines for opto-electronic arrangements and process for their preparation VEB Werk Für Fernsehelektronik im VEB Kombinat Mikroelektronik (DD) 1981-03-18 EP disclosed
US-4073742-A Cyano-substituted biphenyl compounds and liquid crystalline dielectrics containing the same MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-02-14 US disclosed
US-4058478-A P-ALKYLBENZOIC ACID P'-CYANOPHENYL ESTER HOFFMANN-LA ROCHE INC. (US) 1977-11-15 US disclosed
US-4017540-A INSECTICIDES, MITICIDES THE UPJOHN COMPANY (US) 1977-04-12 US disclosed
US-3963311-A Liquid crystal esters HOFFMANN-LA ROCHE INC. (US) 1976-06-15 US disclosed
US-3932661-A Anthelmintic methods employing benzoyl chloride phenylhydrazones THE UPJOHN COMPANY (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795058-B2 Silicon dioxide composite particle with far-infrared radioactivity; precursor of the same and application thereof MSR1, SIK2, FAR1 THRA 1369/4885THRB 1673/4885RARB 2574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.