SCHEMBL158152

SCHEMBL158152

CCCCCc1ccc(C(=O)Cl)cc1

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRA P10827 9/20 0.67
THRB P10828 9/20 0.67
RARB P10826 5/20 0.64
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
ALDH1A1 P00352 2/20 0.62
RARA P10276 1/20 0.62
MAPT P10636 1/20 0.62
MTOR P42345 1/20 0.62
PLA2G1B P04054 3/20 0.58
ATG4B Q9Y4P1 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2180222 0.98 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL1021538 0.98 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL1020543 0.98 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL1021352 0.98 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL8960387 0.98 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL269399 0.98 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL17272985 0.98 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL9431010 0.98 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL8728345 0.98 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL2385561 0.98 THRA (0.70) THRATHRBRARBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102067835-A 4-pentylbenzoyl chloride miticide and preparation method thereof BEIJING AGRICULTURAL COLLEGE 2011-05-25 CN claimed
US-20250387373-A1 SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS OHIO STATE INNOVATION FOUNDATION (US) 2025-12-25 US disclosed
US-12390449-B2 Substituted 2-aminobenzimidazoles analogs as antibiofilm agents OHIO STATE INNOVATION FOUNDATION (US) 2025-08-19 US disclosed
CN-118027395-B Coating material, preparation method and application thereof, and lithium battery diaphragm 安徽壹石通材料科学研究院有限公司 2025-04-29 CN disclosed
WO-2024235876-A1 PYRIDOPYRIMIDINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS FERNANDEZ CAPETILLO OSCAR (SE) 2024-11-21 WO disclosed
US-20240156788-A1 SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS NORTH CAROLINA STATE UNIVERSITY 2024-05-16 US disclosed
CN-118027395-A Coating material, preparation method and application thereof, and lithium battery diaphragm 安徽壹石通材料科学研究院有限公司 2024-05-14 CN disclosed
US-11883384-B2 Substituted 2-aminobenzimidazoles analogs as antibiofilm agents OHIO STATE INNOVATION FOUNDATION (US) 2024-01-30 US disclosed
US-20230138583-A1 SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS OHIO STATE INNOVATION FOUNDATION 2023-05-04 US disclosed
CN-113582969-B Application of acylthiourea compound in preparation of anti-enterovirus drugs 武汉大学 2022-06-14 CN disclosed
US-4167489-A AN IMINE-ESTER AROMATIC COMPOUND BBC BROWN BOVERI & COMPANY, LIMITED (CH) 1979-09-11 US disclosed
US-4122116-A HERBICIDES DEUTSCHE GOLD- UND SILBER- SCHEIDEANSTALT VORMALS ROESSLER (DE) 1978-10-24 US disclosed
US-4108875-A REACTING ACYL HALIDE WITH AN ALKALI METAL CYANIDE AND A COPPER(I) SALT IN THE PRESENCE OF A CARBOXYLIC ACID NITRILE WITH HEATING DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1978-08-22 US disclosed
US-4108877-A REACTING ACYL HALIDE WITH COPPER CYANIDE WITH HEATING IN THE PRESENCE OF A CARBOXYLIC ACID NITRILE AND AN ORGANIC SOLVENT DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1978-08-22 US disclosed
US-4058477-A P-((P-ALKYLBENZYLIDEN)AMINO)-BENZONITRILE HOFFMANN-LA ROCHE INC. (US) 1977-11-15 US disclosed
US-4058478-A P-ALKYLBENZOIC ACID P'-CYANOPHENYL ESTER HOFFMANN-LA ROCHE INC. (US) 1977-11-15 US disclosed
US-3975286-A Low voltage actuated field effect liquid crystals compositions and method of synthesis BECKMAN INSTRUMENTS, INC. (US) 1976-08-17 US disclosed
US-3971824-A LIQUID CRYSTAL EASTMAN KODAK COMPANY (US) 1976-07-27 US disclosed
US-3963313-A Liquid crystal Schiffs bases HOFFMANN-LA ROCHE INC. (US) 1976-06-15 US disclosed
US-3963311-A Liquid crystal esters HOFFMANN-LA ROCHE INC. (US) 1976-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12390449-B2 Substituted 2-aminobenzimidazoles analogs as antibiofilm agents ITGB3, ITGB2, ITGAM THRA 1068/4885THRB 155/4885RARB 3968/4885
US-20250387373-A1 SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS ITGB3, CFTR, Q6ZSR9 THRA 116/4885THRB 6/4885RARB 2623/4885
US-20230138583-A1 SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS ITGB3, ITGB2, ITGAM THRA 1068/4885THRB 155/4885RARB 3968/4885
US-11883384-B2 Substituted 2-aminobenzimidazoles analogs as antibiofilm agents ITGB3, ITGB2, ITGAM THRA 1068/4885THRB 155/4885RARB 3968/4885
US-20240156788-A1 SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS ITGB3, ITGB2, ITGAM THRA 1068/4885THRB 155/4885RARB 3968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.